Protein: NCK1
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)

Gene: NCK1
Organism: Mus musculus
Interactions: 22
UniProt ID: Q99M51

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000164 - protein phosphatase type 1 complex
GO:0004860 - protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021485

DOK1
Docking protein 1

2

20

Small-scale

0.811

High

362454

ABL1
Tyrosine-protein kinase ABL1

2

20

Small-scale

0.777

High

267122

DOK2
Docking protein 2

1

20

High-throughput

0.691

High

236934

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.665

High

1189758

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

12

High-throughput

0.646

High

205473

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.618

High

813529

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

1221486

LCP2
Lymphocyte cytosolic protein 2

1

20

Small-scale

0.618

High

651564

CBL
E3 ubiquitin-protein ligase CBL

2

20

Small-scale

0.584

High

1000090

WASP
Actin nucleation-promoting factor WAS

2

20

Small-scale

0.576

High

1021161

DAB1
Disabled homolog 1

1

20

Small-scale

0.479

High

1188902

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

312746

PAK1
Serine/threonine-protein kinase PAK 1

1

20

High-throughput

0.457

High

571218

CALR
Calreticulin

1

1

High-throughput

0.457

High

1221433

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

20

High-throughput

0.457

High

1224648

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

20

High-throughput

0.457

High

1317221

WIPF1
WAS/WASL-interacting protein family member 1

1

20

High-throughput

0.457

High

1408862

PSRC1
Proline/serine-rich coiled-coil protein 1

1

1

High-throughput

0.457

High

1408863

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

10

High-throughput

0.457

High

1253558

Q6ZQG6
MKIAA0198 protein

1

0

High-throughput

0.438

High

86325

B9EKI5
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.417

High

1021947

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

High-throughput

0.417

High


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Last updated: 11Aug2025