HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: S12A1 (Q13621)
Solute carrier family 12 member 1 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (BSC1) (Kidney-specific Na-K-Cl symporter) (Na-K-2Cl cotransporter 2) (NKCC2)
Gene: SLC12A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 1099
+	Hs
		343944 HS74L_HUMAN (1-840): 0: 961: 63.21		S12A1_HUMAN (1-1099): 0: 1130: 100.00
+	Hs
		1115502 HS105_HUMAN (1-840): 0: 939: 62.95		S12A1_HUMAN (1-1099): 0: 1130: 100.00
+	Hs
		761607 HSP74_HUMAN (1-840): 0: 996: 100.00		S12A3_HUMAN (58-1098): 0: 912: 50.33
+	Hs
		343923 HS74L_HUMAN (1-840): 0: 961: 63.21		S12A3_HUMAN (58-1098): 0: 912: 50.33
+	Hs
		933531 HS105_HUMAN (1-840): 0: 939: 62.95		S12A3_HUMAN (58-1098): 0: 912: 50.33
+	Hs
		761945 HSP74_HUMAN (1-840): 0: 996: 100.00		S12A7_HUMAN (58-1099): 0: 754: 21.22
+	Hs
		761918 HSP74_HUMAN (1-840): 0: 996: 100.00		S12A6_HUMAN (43-1099): 0: 743: 21.88
+	Hs
		344036 HS74L_HUMAN (1-840): 0: 961: 63.21		S12A6_HUMAN (43-1099): 0: 743: 21.88
+	Hs
		1365260 HS105_HUMAN (1-840): 0: 939: 62.95		S12A6_HUMAN (43-1099): 0: 743: 21.88
+	Hs
		761931 HSP74_HUMAN (1-840): 0: 996: 100.00		S12A4_HUMAN (60-1099): 1.04e-155: 493: 17.38
+	Hs
		344044 HS74L_HUMAN (1-840): 0: 961: 63.21		S12A4_HUMAN (60-1099): 1.04e-155: 493: 17.38
+	Hs
		1365271 HS105_HUMAN (1-840): 0: 939: 62.95		S12A4_HUMAN (60-1099): 1.04e-155: 493: 17.38
+	Hs
		761395 HS71L_HUMAN (564-691): 4.11e-18: 91.2: 22.48		S12A1_HUMAN (1-1099): 0: 1130: 100.00
+	Hs
		536832 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		S12A3_HUMAN (58-1098): 0: 912: 50.33
+	Hs
		761356 HS71L_HUMAN (564-691): 4.11e-18: 91.2: 22.48		S12A3_HUMAN (58-1098): 0: 912: 50.33
+	Sc
		673411 HSP7F_YEAST (5-697): 5.72e-137: 424: 37.61		AGP1_YEAST (68-681): 3.61e-119: 383: 13.46
+	Sc
		741936 HSP7F_YEAST (5-697): 5.72e-137: 424: 37.61		GNP1_YEAST (85-657): 6.03e-109: 356: 13.51
+	Hs
		537836 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		S12A9_HUMAN (175-1089): 0: 557: 25.03
+	Sc
		742077 HSP7F_YEAST (5-697): 5.72e-137: 424: 37.61		DIP5_YEAST (192-625): 3.09e-61: 222: 16.74
+	Hs
		538125 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		S12A4_HUMAN (60-1099): 1.04e-155: 493: 17.38