Interactor 1: SKI2 (P35207)
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2)
Gene: SKI2

Interactor 2: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 11805826, 16429126
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~DSHCT, DSHCT~Helicase_C, Helicase_C~Helicase_C, DEAD~MTR4-like_stalk, DEAD~Ski2_N
Common GO terms GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0016887 - ATP hydrolysis activity
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1287
Sc

1 773
+ Sc
+ Sc
+ Sc
+ Sc
+ Sp
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025