Interactor 1: AFG3 (P39925)
Mitochondrial inner membrane m-AAA protease component YTA10 (EC 3.4.24.-) (EC 3.6.-.-) (ATPase family gene 3 protein) (Tat-binding homolog 10)
Gene: AFG3
Interactor 2: YTA12 (P40341)
Mitochondrial inner membrane m-AAA protease component YTA12 (EC 3.4.24.-) (EC 3.6.-.-) (Tat-binding homolog 12)
Gene: YTA12
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.965 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8681382, 9707443, 16429126, 21147776, 37968396, 32051233, 16239145, 19748354, 21610694 |
| Identification Methods | biophysical, affinity chromatography technology, x-ray crystallography, cross-linking study, biochemical, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~AAA, AAA~AAA_lid_3, AAA~Peptidase_M41, AAA_lid_3~AAA_lid_3, AAA_lid_3~Peptidase_M41, FtsH_ext~FtsH_ext, Peptidase_M41~Peptidase_M41 |
| Common GO terms | GO:0004176 - ATP-dependent peptidase activity GO:0004222 - metalloendopeptidase activity GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane and 9 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
