HitPredict

Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: Q8TBB7 (Q8TBB7)
DDB1 and CUL4 associated factor 5 (WD repeat domain 22, isoform CRA_d) (WDR22 protein)
Gene: DCAF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 326
+	Hs
		772005 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		DCAF8_HUMAN (3-319): 4.16e-75: 243: 20.58
+	Hs
		772056 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		WDTC1_HUMAN (42-291): 2.69e-50: 179: 24.90
+	Hs
		771895 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		RACK1_HUMAN (32-222): 1.22e-27: 111: 16.46
+	Hs
		772142 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		KTNB1_HUMAN (174-315): 2.34e-18: 87.6: 15.96