Protein: K1C9
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)

Gene: K1C9, KRT9
Organism: Homo sapiens
Interactions: 182
UniProt ID: P35527

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

771983

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

771994

CUL4B
Cullin-4B

2

20

High-throughput

0.611

High

413307

P53
Cellular tumor antigen p53

2

8

Small-scale

0.584

High

563322

CFTR
Cystic fibrosis transmembrane conductance regulator

2

20

Small-scale

0.571

High

619552

VCAM1
Vascular cell adhesion protein 1

2

6

High-throughput

0.571

High

387244

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.536

High

389973

ALBU
Albumin

1

8

High-throughput

0.536

High

771962

IF4A3
Eukaryotic initiation factor 4A-III

1

17

High-throughput

0.536

High

771990

CUL1
Cullin-1

1

20

High-throughput

0.536

High

771991

CUL2
Cullin-2

1

20

High-throughput

0.536

High

771992

CUL3
Cullin-3

1

20

High-throughput

0.536

High

771993

CUL4A
Cullin-4A

1

20

High-throughput

0.536

High

772000

FL2D
Pre-mRNA-splicing regulator WTAP

1

8

High-throughput

0.536

High

772004

NEDD8
Ubiquitin-like protein NEDD8

1

6

High-throughput

0.536

High

772024

CSN6
COP9 signalosome complex subunit 6

1

10

High-throughput

0.536

High

772025

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

13

High-throughput

0.536

High

772026

TLK2
Serine/threonine-protein kinase tousled-like 2

1

13

High-throughput

0.536

High

772027

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.536

High

772033

RIN3
Ras and Rab interactor 3

1

3

High-throughput

0.536

High

772039

CSN5
COP9 signalosome complex subunit 5

1

18

High-throughput

0.536

High

772040

CUL5
Cullin-5

1

20

High-throughput

0.536

High

772047

DCNL1
DCN1-like protein 1

1

2

High-throughput

0.536

High

772067

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

13

High-throughput

0.536

High

772013

RC3H1
Roquin-1

2

12

High-throughput

0.533

High

555909

CADH1
Cadherin-1

1

3

Small-scale

0.515

High

690781

1433T
14-3-3 protein theta

1

18

High-throughput

0.515

High

692870

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.515

High

185477

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

771984

UBE3A
Ubiquitin-protein ligase E3A

1

5

Small-scale

0.501

High

772034

MIPT3
TRAF3-interacting protein 1

1

1

Small-scale

0.489

High

771982

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

10

High-throughput

0.484

High

772041

WBP2
WW domain-binding protein 2

1

0

Small-scale

0.480

High

131344

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

10

Small-scale

0.479

High

136309

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.479

High

141344

DDX3X
ATP-dependent RNA helicase DDX3X

1

7

Small-scale

0.479

High

187300

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

12

High-throughput

0.479

High

187902

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

20

Small-scale

0.479

High

209494

SERA
D-3-phosphoglycerate dehydrogenase

1

7

Small-scale

0.479

High

240905

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

257361

PAGE4
P antigen family member 4

1

2

High-throughput

0.479

High

277276

PITX3
Pituitary homeobox 3

1

10

Small-scale

0.479

High

302406

RNF8
E3 ubiquitin-protein ligase RNF8

1

17

High-throughput

0.479

High

319459

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

323205

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

324593

HEXI1
Protein HEXIM1

1

20

High-throughput

0.479

High

335018

ARI2
E3 ubiquitin-protein ligase ARIH2

1

19

High-throughput

0.479

High

353044

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.479

High

362876

EGFR
Epidermal growth factor receptor

1

11

High-throughput

0.479

High

371324

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.479

High

377984

TNFA
Tumor necrosis factor

1

5

High-throughput

0.479

High

378959

PIGR
Polymeric immunoglobulin receptor

1

1

Small-scale

0.479

High

389093

FINC
Fibronectin

1

7

High-throughput

0.479

High

405844

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

425346

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

443014

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

4

Small-scale

0.479

High

458301

ADRB2
Beta-2 adrenergic receptor

1

1

High-throughput

0.479

High

482338

F16P1
Fructose-1,6-bisphosphatase 1

1

6

High-throughput

0.479

High

484958

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.479

High

521227

ARAF
Serine/threonine-protein kinase A-Raf

1

5

High-throughput

0.479

High

565192

ITA4
Integrin alpha-4

1

4

High-throughput

0.479

High

590821

TIMP2
Metalloproteinase inhibitor 2

1

9

High-throughput

0.479

High

612153

ARF4
ADP-ribosylation factor 4

1

6

High-throughput

0.479

High

629602

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

651186

CBL
E3 ubiquitin-protein ligase CBL

1

12

High-throughput

0.479

High

668518

APC
Adenomatous polyposis coli protein

1

10

Small-scale

0.479

High

711255

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

714772

EF1D
Elongation factor 1-delta

1

2

Small-scale

0.479

High

771960

ARL2
ADP-ribosylation factor-like protein 2

1

8

High-throughput

0.479

High

771961

TRI23
E3 ubiquitin-protein ligase TRIM23

1

10

High-throughput

0.479

High

771963

ARL1
ADP-ribosylation factor-like protein 1

1

7

High-throughput

0.479

High

771964

EPS15
Epidermal growth factor receptor substrate 15

1

20

High-throughput

0.479

High

771965

MAGA3
Melanoma-associated antigen 3

1

8

Small-scale

0.479

High

771966

NKX21
Homeobox protein Nkx-2.1

1

3

High-throughput

0.479

High

771967

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

771968

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

771970

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

771973

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.479

High

771974

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

12

High-throughput

0.479

High

771976

MGN
Protein mago nashi homolog

1

5

High-throughput

0.479

High

771977

WDR5
WD repeat-containing protein 5

1

6

High-throughput

0.479

High

771978

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.479

High

771979

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

771980

ARF5
ADP-ribosylation factor 5

1

6

High-throughput

0.479

High

771981

H33
Histone H3.3

1

2

High-throughput

0.479

High

771987

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

771989

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

8

High-throughput

0.479

High

771995

DX39B
Spliceosome RNA helicase DDX39B

1

20

Small-scale

0.479

High

771997

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.479

High

771998

CUL7
Cullin-7

1

7

High-throughput

0.479

High

772001

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

9

High-throughput

0.479

High

772002

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

19

High-throughput

0.479

High

772005

EZH2
Histone-lysine N-methyltransferase EZH2

1

15

High-throughput

0.479

High

772007

LARP7
La-related protein 7

1

16

High-throughput

0.479

High

772008

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

9

High-throughput

0.479

High

772009

MIDN
Midnolin

1

3

High-throughput

0.479

High

772010

EMC4
ER membrane protein complex subunit 4

1

4

High-throughput

0.479

High

772014

OTU1
Ubiquitin thioesterase OTU1

1

9

High-throughput

0.479

High

772015

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

772016

PRP8
Pre-mRNA-processing-splicing factor 8

1

11

High-throughput

0.479

High

772019

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

772020

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

772023

MEPCE
7SK snRNA methylphosphate capping enzyme

1

15

High-throughput

0.479

High

772029

RHG24
Rho GTPase-activating protein 24

1

8

High-throughput

0.479

High

772032

TNIP2
TNFAIP3-interacting protein 2

1

8

High-throughput

0.479

High

772035

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.479

High

772036

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

12

High-throughput

0.479

High

772037

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.479

High

772038

TANK
TRAF family member-associated NF-kappa-B activator

1

3

High-throughput

0.479

High

772043

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

10

Small-scale

0.479

High

772044

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

772045

AP2M1
AP-2 complex subunit mu

1

9

High-throughput

0.479

High

772046

RNF31
E3 ubiquitin-protein ligase RNF31

1

17

High-throughput

0.479

High

772051

TRIB3
Tribbles homolog 3

1

3

Small-scale

0.479

High

772052

NECD
Necdin

1

8

High-throughput

0.479

High

772054

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

4

High-throughput

0.479

High

772055

ACE2
Angiotensin-converting enzyme 2

1

8

High-throughput

0.479

High

772056

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

9

High-throughput

0.479

High

772057

TRI31
E3 ubiquitin-protein ligase TRIM31

1

20

High-throughput

0.479

High

772060

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.479

High

772062

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

772063

ATG5
Autophagy protein 5

1

7

High-throughput

0.479

High

772065

RC3H2
Roquin-2

1

19

High-throughput

0.479

High

772066

NMRL1
NmrA-like family domain-containing protein 1

1

2

High-throughput

0.479

High

772068

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

15

High-throughput

0.479

High

772069

ANLN
Anillin

1

12

High-throughput

0.479

High

772070

SAR1A
Small COPII coat GTPase SAR1A

1

15

High-throughput

0.479

High

772071

RNF12
E3 ubiquitin-protein ligase RLIM

1

20

High-throughput

0.479

High

772072

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

772073

HDAC6
Protein deacetylase HDAC6

1

20

High-throughput

0.479

High

772075

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

772076

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

772077

FBXL4
F-box/LRR-repeat protein 4

1

1

Small-scale

0.479

High

772078

FAF1
FAS-associated factor 1

1

2

High-throughput

0.479

High

772080

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

772081

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

12

Small-scale

0.479

High

772082

SAR1B
Small COPII coat GTPase SAR1B

1

11

High-throughput

0.479

High

290874

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.458

High

766242

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

771999

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

772012

ARM12
Armadillo repeat-containing protein 12

1

0

Small-scale

0.458

High

772042

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

143402

E2F3
Transcription factor E2F3

1

1

Small-scale

0.445

High

327832

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

379223

IGHG1
Immunoglobulin heavy constant gamma 1

1

12

High-throughput

0.445

High

379492

IGHM
Immunoglobulin heavy constant mu

1

12

High-throughput

0.445

High

379621

IGHA1
Immunoglobulin heavy constant alpha 1

1

12

High-throughput

0.445

High

529214

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

771975

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

771985

LG3BP
Galectin-3-binding protein

1

10

High-throughput

0.445

High

771988

CTBP1
C-terminal-binding protein 1

1

7

High-throughput

0.445

High

771996

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

9

High-throughput

0.445

High

772003

T22D1
TSC22 domain family protein 1

1

1

Small-scale

0.445

High

772011

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

772028

SULF2
Extracellular sulfatase Sulf-2

1

12

High-throughput

0.445

High

772059

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

20

High-throughput

0.445

High

772061

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

772064

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.445

High

105455

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

293294

CD123
Translation initiation factor eIF2 assembly protein

1

13

High-throughput

0.437

High

635240

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

771969

ARL4D
ADP-ribosylation factor-like protein 4D

1

10

High-throughput

0.437

High

771971

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

771972

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

771986

ARL16
ADP-ribosylation factor-like protein 16

1

12

High-throughput

0.437

High

772006

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

3

Small-scale

0.437

High

772017

FBX42
F-box only protein 42

1

3

High-throughput

0.437

High

772018

LRC31
Leucine-rich repeat-containing protein 31

1

11

High-throughput

0.437

High

772021

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.437

High

772022

KCTD9
BTB/POZ domain-containing protein KCTD9

1

16

High-throughput

0.437

High

772030

ARL10
ADP-ribosylation factor-like protein 10

1

12

High-throughput

0.437

High

772048

DIRA2
GTP-binding protein Di-Ras2

1

3

Small-scale

0.437

High

772049

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

772050

ARL5B
ADP-ribosylation factor-like protein 5B

1

8

High-throughput

0.437

High

772058

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

772074

KS6B2
Ribosomal protein S6 kinase beta-2

1

7

High-throughput

0.437

High

772079

AAR2
Protein AAR2 homolog

1

6

High-throughput

0.437

High

294663

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

772053

SH3G3
Endophilin-A3

1

20

High-throughput

0.417

High

947

SIM26
Small integral membrane protein 26

1

5

High-throughput

0.407

High

155379

AQP7
Aquaporin-7

1

7

Small-scale

0.407

High

653160

HEMH
Ferrochelatase, mitochondrial

1

4

High-throughput

0.407

High

772031

FNDC5
Fibronectin type III domain-containing protein 5

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025