Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1
Interactor 2: PHIP (Q8VDD9)
PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (Neuronal differentiation-related protein) (NDRP) (WD repeat-containing protein 11)
Gene: PHIP
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11018022 |
| Identification Methods | coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~WD40 |
| Common GO terms | GO:0005634 - nucleus GO:0008286 - insulin receptor signaling pathway |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
