HitPredict

Interactor 1: ARL4A (P40617)
ADP-ribosylation factor-like protein 4A
Gene: ARL4A

Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	17804820
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arf~PH, Arf~Sec7
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 400
+	Hs
		913064 ARF6_HUMAN (8-184): 9.01e-85: 249: 43.50		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00
+	Rn
		913236 ARF6_RAT (8-184): 9.01e-85: 249: 43.50		CYH2_RAT (1-400): 9.2e-180: 507: 99.25
+	Hs
		830780 ARL4D_HUMAN (1-200): 9.72e-81: 240: 60.20		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00
+	Mm
		913234 ARF6_MOUSE (8-184): 9.01e-85: 249: 43.50		CYH1_MOUSE (2-397): 5.55e-177: 500: 82.58
+	Hs
		912917 ARF6_HUMAN (8-184): 9.01e-85: 249: 43.50		CYH1_HUMAN (2-397): 5.27e-176: 498: 83.08
+	Hs
		950545 ARF1_HUMAN (1-190): 6.51e-67: 204: 41.58		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00
+	Hs
		912959 ARF6_HUMAN (8-184): 9.01e-85: 249: 43.50		IQEC1_HUMAN (27-396): 4.37e-109: 344: 26.20
+	Hs
		913002 ARF6_HUMAN (8-184): 9.01e-85: 249: 43.50		PSD4_HUMAN (1-389): 2.58e-107: 341: 21.95
+	Hs
		913219 ARF6_HUMAN (8-184): 9.01e-85: 249: 43.50		BIG1_HUMAN (3-268): 4.63e-97: 319: 37.13
+	Dm
		778393 ARF6_DROME (8-184): 6.03e-83: 245: 44.07		Q6U9V3_DROME (61-366): 8.42e-98: 318: 30.36
+	Hs
		950731 ARF5_HUMAN (9-189): 6.93e-87: 255: 42.54		PSD3_HUMAN (91-389): 6.34e-92: 299: 22.69
+	Sc
		503097 ARF1_YEAST (9-189): 1.21e-86: 254: 40.88		GEA2_YEAST (9-364): 1.68e-88: 294: 24.54
+	Hs
		913147 ARF6_HUMAN (8-184): 9.01e-85: 249: 43.50		PSD3_HUMAN (91-389): 6.34e-92: 299: 22.69
+	Sc
		502942 ARF1_YEAST (9-189): 1.21e-86: 254: 40.88		SEC7_YEAST (9-249): 2.65e-86: 288: 38.62
+	Dm
		897468 ARF1_DROME (1-191): 1.2e-66: 204: 41.89		Q9VJW1_DROME (5-285): 9.34e-91: 301: 35.66
+	Sc
		350883 YPT1_YEAST (21-200): 1.12e-65: 202: 24.31		GEA2_YEAST (9-364): 1.68e-88: 294: 24.54
+	Sc
		350838 YPT1_YEAST (21-200): 1.12e-65: 202: 24.31		SEC7_YEAST (9-249): 2.65e-86: 288: 38.62
+	Dm
		53567 O18332_DROME (21-199): 2.85e-67: 206: 23.89		A1Z8W9_DROME (49-271): 2.23e-80: 271: 33.33
+	Dm
		53572 ARF1_DROME (1-191): 1.2e-66: 204: 41.89		A1Z8W9_DROME (49-271): 2.23e-80: 271: 33.33
+	Hs
		592409 RAB5A_HUMAN (1-200): 4.94e-66: 203: 19.40		GBF1_HUMAN (51-257): 3.18e-80: 270: 37.26