HitPredict

Interactor 1: TRI14 (Q14142)
Tripartite motif-containing protein 14
Gene: TRIM14

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	28476934
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 232
+	Hs
		585075 TRI39_HUMAN (1-442): 7.2e-131: 389: 25.22		RO52_HUMAN (22-227): 1.26e-41: 149: 13.30
+	Hs
		1283424 TRI39_HUMAN (1-442): 7.2e-131: 389: 25.22		RN166_HUMAN (1-224): 1.46e-42: 145: 30.83
+	Hs
		1336382 TRI39_HUMAN (1-442): 7.2e-131: 389: 25.22		TRI39_HUMAN (28-229): 3.66e-38: 140: 16.90
+	Hs
		585033 RO52_HUMAN (1-442): 3.23e-116: 350: 22.32		RN125_HUMAN (1-232): 1.03e-55: 179: 100.00
+	Hs
		1336392 TRI39_HUMAN (1-442): 7.2e-131: 389: 25.22		TRI17_HUMAN (22-226): 6.96e-35: 131: 15.32
+	Hs
		536726 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		RO52_HUMAN (22-227): 1.26e-41: 149: 13.30
+	Hs
		584870 RO52_HUMAN (1-442): 3.23e-116: 350: 22.32		RO52_HUMAN (22-227): 1.26e-41: 149: 13.30
+	Hs
		1024674 TRI14_HUMAN (1-442): 5.79e-122: 363: 100.00		TRAF3_HUMAN (5-175): 4.42e-33: 127: 19.89
+	Hs
		1252493 TRI39_HUMAN (1-442): 7.2e-131: 389: 25.22		LNX1_HUMAN (28-142): 7.17e-24: 101: 24.17
+	Hs
		537046 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		TRI31_HUMAN (22-226): 5.82e-36: 133: 12.50
+	Hs
		536970 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		TRI43_HUMAN (24-229): 1.32e-35: 132: 15.09
+	Hs
		536980 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		TRI11_HUMAN (22-215): 2.41e-33: 126: 15.50
+	Hs
		585057 RO52_HUMAN (1-442): 3.23e-116: 350: 22.32		TRI31_HUMAN (22-226): 5.82e-36: 133: 12.50
+	Hs
		536717 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		TRI27_HUMAN (22-228): 7.77e-33: 125: 15.49
+	Hs
		129529 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		TRAF5_HUMAN (8-176): 3.95e-29: 116: 23.81
+	Hs
		1049092 TRI14_HUMAN (1-442): 5.79e-122: 363: 100.00		LNX1_HUMAN (28-142): 7.17e-24: 101: 24.17
+	Hs
		536942 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		LNX1_HUMAN (28-142): 7.17e-24: 101: 24.17
+	Hs
		585019 RO52_HUMAN (1-442): 3.23e-116: 350: 22.32		LNX1_HUMAN (28-142): 7.17e-24: 101: 24.17
+	Hs
		536850 TRI27_HUMAN (1-442): 2.34e-118: 357: 23.16		LONF1_HUMAN (32-81): 1.24e-10: 62.4: 36.00