HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: MET14 (Q9HCE5)
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14 (Methyltransferase-like protein 14) (hMETTL14)
Gene: METTL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29507755
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 456
+	Hs
		437351 K2C8_HUMAN (150-535): 1.3e-143: 427: 59.33		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		475780 K2C7_HUMAN (86-542): 4.84e-131: 395: 52.62		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		407536 K2C1_HUMAN (143-509): 1.14e-110: 348: 71.94		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		407343 K2C6B_HUMAN (5-510): 2.01e-82: 272: 61.22		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		566457 K2C5_HUMAN (1-494): 1.41e-80: 267: 61.08		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		1135588 K2C72_HUMAN (1-494): 5.11e-76: 253: 55.26		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		618162 K2C4_HUMAN (11-502): 3.26e-72: 243: 59.96		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		1280861 K2C1B_HUMAN (58-509): 1.83e-65: 227: 61.50		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		407487 K2C1_HUMAN (143-509): 1.14e-110: 348: 71.94		MTA70_HUMAN (161-391): 2.47e-88: 282: 29.00
+	Hs
		1287892 KRT84_HUMAN (5-576): 1.24e-102: 326: 44.43		MTA70_HUMAN (161-391): 2.47e-88: 282: 29.00
+	Hs
		566415 K2C5_HUMAN (1-494): 1.41e-80: 267: 61.08		MTA70_HUMAN (161-391): 2.47e-88: 282: 29.00
+	Hs
		385299 K2C6A_HUMAN (5-510): 2.13e-78: 261: 61.22		MTA70_HUMAN (161-391): 2.47e-88: 282: 29.00
+	Hs
		1135578 K2C72_HUMAN (1-494): 5.11e-76: 253: 55.26		MTA70_HUMAN (161-391): 2.47e-88: 282: 29.00
+	Hs
		777511 K22E_HUMAN (1-517): 1.58e-67: 234: 100.00		MTA70_HUMAN (161-391): 2.47e-88: 282: 29.00