HitPredict

Interactor 1: LHS1 (P36016)
Heat shock protein 70 homolog LHS1 (EC 3.6.1.-)
Gene: LHS1

Interactor 2: IPI3 (P53877)
Pre-rRNA-processing protein IPI3 (Involved in processing IST2 protein 3)
Gene: IPI3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.526

Property	Details
Experiments	22875988, 19536198
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 881 Sc			1 555
+	Sc
		779562 LHS1_YEAST (1-881): 0: 993: 100.00		COPA_YEAST (5-320): 2.74e-27: 119: 10.62
+	Hs
		536889 HSP7C_HUMAN (18-682): 0: 805: 19.61		WDR5_HUMAN (2-331): 1.18e-51: 181: 11.05
+	Hs
		536681 HSP7C_HUMAN (18-682): 0: 805: 19.61		LIS1_HUMAN (2-227): 3.33e-39: 149: 12.23
+	Hs
		761452 HS71L_HUMAN (18-688): 0: 824: 19.73		POC1A_HUMAN (2-183): 3.37e-28: 118: 14.49
+	Hs
		600864 HSP76_HUMAN (22-699): 0: 808: 20.71		POC1A_HUMAN (2-183): 3.37e-28: 118: 14.49
+	Hs
		537531 HSP7C_HUMAN (18-682): 0: 805: 19.61		POC1A_HUMAN (2-183): 3.37e-28: 118: 14.49
+	Hs
		536814 HSP7C_HUMAN (18-682): 0: 805: 19.61		COPA_HUMAN (340-527): 4.12e-20: 96.8: 13.83
+	Hs
		537452 HSP7C_HUMAN (18-682): 0: 805: 19.61		WDR5B_HUMAN (419-526): 9.78e-19: 89.6: 10.19
+	Hs
		537821 HSP7C_HUMAN (18-682): 0: 805: 19.61		WDR18_HUMAN (245-486): 1.21e-15: 81.4: 11.54
+	Sc
		524766 HSP71_YEAST (76-574): 4.99e-31: 132: 24.55		IPI3_YEAST (1-555): 1.69e-93: 298: 95.16
+	Hs
		965368 HYOU1_HUMAN (21-481): 2.68e-52: 200: 29.83		WDR5_HUMAN (2-331): 1.18e-51: 181: 11.05
+	Sc
		645759 HSP74_YEAST (76-668): 1.87e-31: 133: 23.32		COPA_YEAST (5-320): 2.74e-27: 119: 10.62
+	Sc
		524709 HSP71_YEAST (76-574): 4.99e-31: 132: 24.55		COPA_YEAST (5-320): 2.74e-27: 119: 10.62
+	Sc
		481705 HSP73_YEAST (76-668): 9.29e-31: 131: 23.71		COPA_YEAST (5-320): 2.74e-27: 119: 10.62
+	Sc
		527306 HSP72_YEAST (76-574): 1.07e-30: 130: 24.45		COPA_YEAST (5-320): 2.74e-27: 119: 10.62
+	Sc
		523201 HSP71_YEAST (76-574): 4.99e-31: 132: 24.55		PWP2_YEAST (3-328): 1.08e-23: 107: 8.29
+	Sc
		526044 HSP72_YEAST (76-574): 1.07e-30: 130: 24.45		PWP2_YEAST (3-328): 1.08e-23: 107: 8.29
+	Sc
		523704 HSP71_YEAST (76-574): 4.99e-31: 132: 24.55		TAF5_YEAST (141-424): 3.85e-18: 90.1: 11.86
+	Sc
		481593 HSP73_YEAST (76-668): 9.29e-31: 131: 23.71		TAF5_YEAST (141-424): 3.85e-18: 90.1: 11.86
+	Sc
		526483 HSP72_YEAST (76-574): 1.07e-30: 130: 24.45		TAF5_YEAST (141-424): 3.85e-18: 90.1: 11.86