Protein: IPI3
Pre-rRNA-processing protein IPI3 (Involved in processing IST2 protein 3)

Gene: IPI3
Organism: Saccharomyces cerevisiae S288C
Interactions: 139
UniProt ID: P53877

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

918939

PESC
Pescadillo homolog

4

4

High-throughput

0.873

High

673583

NLE1
Ribosome assembly protein 4

3

18

Small-scale

0.855

High

806639

RIX1
Pre-rRNA-processing protein RIX1

14

1

Small-scale

0.761

High

682353

SPB4
ATP-dependent rRNA helicase SPB4

2

16

High-throughput

0.754

High

805006

IPI1
Pre-rRNA-processing protein IPI1

5

4

High-throughput

0.716

High

919543

SDA1
Protein SDA1

5

2

Small-scale

0.709

High

816878

NUG1
Nuclear GTP-binding protein NUG1

5

10

Small-scale

0.702

High

924255

BUD20
Bud site selection protein 20

4

1

Small-scale

0.699

High

382257

H4
Histone H4

1

10

High-throughput

0.691

High

924231

NOP15
Ribosome biogenesis protein 15

4

6

High-throughput

0.691

High

923175

NOG2
Nucleolar GTP-binding protein 2

4

10

Small-scale

0.686

High

924244

ARX1
Probable metalloprotease ARX1

4

2

Small-scale

0.686

High

924266

IF6
Eukaryotic translation initiation factor 6

3

2

High-throughput

0.667

High

803902

CIC1
Proteasome-interacting protein CIC1

3

6

High-throughput

0.656

High

924259

MDN1
Midasin

3

11

Small-scale

0.646

High

864179

ALB1
Ribosome biogenesis protein ALB1

3

1

Small-scale

0.640

High

924242

NOG1
Nucleolar GTP-binding protein 1

3

6

Small-scale

0.640

High

924265

CAF1A
Chromatin assembly factor 1 subunit A

1

9

High-throughput

0.621

High

792176

GBLP
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

924235

H3
Histone H3

1

14

High-throughput

0.618

High

924263

DBP10
ATP-dependent RNA helicase DBP10

1

13

High-throughput

0.618

High

924249

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.606

High

924230

IPI3
Pre-rRNA-processing protein IPI3

1

18

High-throughput

0.590

High

750119

MRT4
Ribosome assembly factor MRT4

2

7

Small-scale

0.584

High

782399

RPF2
Ribosome biogenesis protein RPF2

2

2

Small-scale

0.584

High

924260

NOP53
Ribosome biogenesis protein NOP53

2

2

High-throughput

0.584

High

924251

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

11

High-throughput

0.575

High

383828

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.553

High

712638

RL8B
Large ribosomal subunit protein eL8B

1

8

High-throughput

0.553

High

874453

RS12
Small ribosomal subunit protein eS12

1

5

High-throughput

0.553

High

479273

CDC6
Cell division control protein 6

1

1

Small-scale

0.552

High

917140

ATG1
Serine/threonine-protein kinase ATG1

2

9

High-throughput

0.542

High

808768

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

3

High-throughput

0.541

High

827572

RLP7
Ribosome biogenesis protein RLP7

2

9

High-throughput

0.533

High

865456

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.529

High

779563

LHS1
Heat shock protein 70 homolog LHS1

2

20

High-throughput

0.526

High

849998

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.513

High

441210

KAPA
cAMP-dependent protein kinase type 1

1

4

High-throughput

0.501

High

602589

PHO85
Cyclin-dependent protein kinase PHO85

1

6

High-throughput

0.501

High

801882

KSP1
Serine/threonine-protein kinase KSP1

1

5

High-throughput

0.501

High

486275

TBA1
Tubulin alpha-1 chain

1

12

High-throughput

0.500

High

676232

MAS5
Mitochondrial protein import protein MAS5

1

14

High-throughput

0.500

High

924264

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.500

High

912742

NU188
Nucleoporin NUP188

1

0

High-throughput

0.481

High

721398

MCM4
DNA replication licensing factor MCM4

1

3

Small-scale

0.481

High

806868

SKN7
Transcription factor SKN7

1

4

High-throughput

0.481

High

924245

YAP6
AP-1-like transcription factor YAP6

1

1

High-throughput

0.481

High

149889

RS9A
Small ribosomal subunit protein uS4A

1

8

High-throughput

0.479

High

410265

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.479

High

435265

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

436481

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

8

High-throughput

0.479

High

442043

RS14A
Small ribosomal subunit protein uS11A

1

7

High-throughput

0.479

High

512575

RS6A
Small ribosomal subunit protein eS6A

1

6

High-throughput

0.479

High

570100

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.479

High

594496

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

664455

MCM3
DNA replication licensing factor MCM3

1

4

Small-scale

0.479

High

670983

SIS1
Protein SIS1

1

12

High-throughput

0.479

High

674758

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

689587

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.479

High

707831

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

713015

MCM2
DNA replication licensing factor MCM2

1

3

Small-scale

0.479

High

739993

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

3

High-throughput

0.479

High

747978

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

795833

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

818257

NSA2
Ribosome biogenesis protein NSA2

1

3

High-throughput

0.479

High

918040

CGR1
rRNA-processing protein CGR1

1

1

High-throughput

0.479

High

924233

ORC1
Origin recognition complex subunit 1

1

4

Small-scale

0.479

High

924241

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.479

High

924248

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

3

High-throughput

0.479

High

924250

NOC4
Nucleolar complex protein 4

1

5

High-throughput

0.479

High

924253

NOC3
Nucleolar complex-associated protein 3

1

3

Small-scale

0.479

High

924258

RRS1
Regulator of ribosome biosynthesis

1

2

High-throughput

0.479

High

924262

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

639506

RE107
Recombination protein 107

1

0

High-throughput

0.460

High

745661

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.460

High

917725

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.460

High

924234

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

924246

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

924256

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

386815

TBB
Tubulin beta chain

1

9

High-throughput

0.457

High

452946

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.457

High

484786

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.457

High

531373

METK1
S-adenosylmethionine synthase 1

1

3

High-throughput

0.457

High

554951

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.457

High

555123

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

763474

MDJ1
DnaJ homolog 1, mitochondrial

1

12

High-throughput

0.457

High

524766

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

545810

SSB1
Ribosome-associated molecular chaperone SSB1

1

19

High-throughput

0.445

High

548919

SCH9
Serine/threonine-protein kinase SCH9

1

3

High-throughput

0.445

High

804356

SSZ1
Ribosome-associated complex subunit SSZ1

1

13

High-throughput

0.445

High

819431

SSB2
Ribosome-associated molecular chaperone SSB2

1

19

High-throughput

0.445

High

737014

CDC3
Cell division control protein 3

1

3

High-throughput

0.439

High

758129

CASP
Protein CASP

1

11

High-throughput

0.439

High

815042

SNF7
Vacuolar-sorting protein SNF7

1

7

High-throughput

0.439

High

817746

TSC11
Target of rapamycin complex 2 subunit TSC11

1

6

High-throughput

0.439

High

924092

CNM67
Chaotic nuclear migration protein 67

1

8

High-throughput

0.439

High

924232

NST1
Stress response protein NST1

1

12

High-throughput

0.439

High

924236

DID2
Vacuolar protein-sorting-associated protein 46

1

2

High-throughput

0.439

High

924243

BUL2
Ubiquitin ligase-binding protein BUL2

1

2

High-throughput

0.439

High

827005

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

High-throughput

0.438

High

884430

CTR1
Copper transport protein CTR1

1

0

High-throughput

0.438

High

924261

YP022
Zinc finger protein YPR022C

1

0

High-throughput

0.438

High

432657

RL7A
Large ribosomal subunit protein uL30A

1

9

High-throughput

0.437

High

432893

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.437

High

433259

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.437

High

433771

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.437

High

436093

RS13
Small ribosomal subunit protein uS15

1

5

High-throughput

0.437

High

455193

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

503171

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.437

High

504345

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

511253

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.437

High

511464

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.437

High

513143

RS8A
Small ribosomal subunit protein eS8A

1

5

High-throughput

0.437

High

514764

RS18A
Small ribosomal subunit protein uS13A

1

4

High-throughput

0.437

High

579845

HSC82
ATP-dependent molecular chaperone HSC82

1

12

High-throughput

0.437

High

689095

RL16A
Large ribosomal subunit protein uL13A

1

5

High-throughput

0.437

High

745098

AFG2
ATPase family gene 2 protein

1

7

High-throughput

0.437

High

747506

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

753510

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.437

High

778465

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

802307

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.437

High

808531

TEM1
Protein TEM1

1

4

High-throughput

0.437

High

812540

LAA1
AP-1 accessory protein LAA1

1

5

High-throughput

0.437

High

820933

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.437

High

924237

RL34A
Large ribosomal subunit protein eL34A

1

2

High-throughput

0.437

High

924239

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

924252

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

924254

RLP24
Ribosome biogenesis protein RLP24

1

2

High-throughput

0.437

High

924257

RS10A
Small ribosomal subunit protein eS10A

1

6

High-throughput

0.437

High

619374

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.417

High

746143

PEP12
Syntaxin PEP12

1

2

High-throughput

0.417

High

618957

IRA2
Inhibitory regulator protein IRA2

1

4

High-throughput

0.407

High

752580

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.407

High

823162

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.282

High

924247

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

792554

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.249

Low

924238

SPR6
Sporulation-specific protein

1

0

High-throughput

0.238

Low

924240

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025