HitPredict

Interactor 1: LONM (P36775)
Lon protease homolog, mitochondrial (EC 3.4.21.53)
Gene: PIM1

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1133 Sc			1 993
+	Sc
		740144 LONM_YEAST (1-1133): 0: 930: 100.00		RPN2_YEAST (52-815): 2.97e-177: 542: 15.54
+	Hs
		91853 C9JUP7_HUMAN (274-881): 2.07e-129: 415: 12.86		PSMD2_HUMAN (2-989): 0: 1010: 34.61
+	Hs
		934554 TERA_HUMAN (274-881): 9.06e-128: 412: 12.86		PSMD2_HUMAN (2-989): 0: 1010: 34.61
+	Sc
		679646 CDC48_YEAST (570-1051): 6.42e-74: 264: 12.02		RPN1_YEAST (1-993): 0: 1053: 100.00
+	Sc
		803632 PRS10_YEAST (596-855): 4.31e-34: 138: 19.49		RPN1_YEAST (1-993): 0: 1053: 100.00
+	Hs
		975389 PRS10_HUMAN (618-855): 1.1e-44: 168: 21.83		PSMD2_HUMAN (2-989): 0: 1010: 34.61
+	Hs
		935035 TERA_HUMAN (274-881): 9.06e-128: 412: 12.86		PSMD1_HUMAN (52-925): 0: 709: 13.42
+	At
		1444844 PS10B_ARATH (626-854): 1.81e-43: 165: 22.63		PSD2A_ARATH (38-992): 0: 925: 33.61
+	Dm
		1464890 Q9V405_DROME (443-851): 1.46e-96: 315: 16.98		Q9VW54_DROME (1-989): 0: 738: 33.30
+	Sp
		267649 PRS10_SCHPO (626-855): 4.83e-40: 154: 20.49		RPN1_SCHPO (5-988): 0: 871: 37.71
+	Dm
		1464086 Q9V405_DROME (443-851): 1.46e-96: 315: 16.98		PSMD1_DROME (52-925): 0: 664: 13.63
+	Dm
		1487645 Q9W414_DROME (602-855): 6.18e-51: 186: 21.82		Q9VW54_DROME (1-989): 0: 738: 33.30
+	Dm
		1486180 Q9VTQ9_DROME (626-855): 5.37e-46: 172: 22.54		Q9VW54_DROME (1-989): 0: 738: 33.30
+	Hs
		975490 PRS10_HUMAN (618-855): 1.1e-44: 168: 21.83		PSMD1_HUMAN (52-925): 0: 709: 13.42
+	Dm
		1464104 Q9W414_DROME (602-855): 6.18e-51: 186: 21.82		PSMD1_DROME (52-925): 0: 664: 13.63
+	Hs
		700 PRS10_HUMAN (618-855): 1.1e-44: 168: 21.83		A0A087WW66_HUMAN (52-925): 0: 645: 13.34
+	Sc
		679497 CDC48_YEAST (570-1051): 6.42e-74: 264: 12.02		RPN2_YEAST (52-815): 2.97e-177: 542: 15.54
+	Sc
		740197 PRS10_YEAST (596-855): 4.31e-34: 138: 19.49		RPN2_YEAST (52-815): 2.97e-177: 542: 15.54