HitPredict

Interactor 1: KI2L2 (P43627)
Killer cell immunoglobulin-like receptor 2DL2 (CD158 antigen-like family member B1) (Natural killer-associated transcript 6) (NKAT-6) (p58 natural killer cell receptor clone CL-43) (p58 NK receptor CL-43) (CD antigen CD158b1)
Gene: KIR2DL2

Interactor 2: KI3L1 (P43629)
Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e)
Gene: KIR3DL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ig~ig
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 348 Hs			1 444
+	Hs
		798136 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00
+	Hs
		798168 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66
+	Hs
		798235 KI3S1_HUMAN (1-346): 8.59e-72: 229: 31.23		KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00
+	Hs
		798164 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI2S2_HUMAN (1-241): 9.82e-45: 159: 39.22
+	Hs
		798169 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI2S3_HUMAN (1-241): 1.24e-41: 151: 37.65
+	Hs
		798135 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI2L1_HUMAN (1-233): 1.07e-40: 150: 39.17
+	Hs
		798142 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		KI2S3_HUMAN (1-241): 1.24e-41: 151: 37.65
+	Hs
		1232785 LIRB4_HUMAN (1-324): 1.6e-77: 246: 29.20		LIRB2_HUMAN (1-444): 6.31e-57: 199: 29.94
+	Hs
		252781 LIRB3_HUMAN (1-336): 1.47e-70: 233: 26.02		LIRA6_HUMAN (1-442): 4.2e-60: 205: 26.75
+	Hs
		1232784 LIRB2_HUMAN (17-348): 2.58e-53: 186: 28.70		LIRA3_HUMAN (1-342): 1.66e-71: 234: 35.06
+	Hs
		1235887 LIRB1_HUMAN (17-348): 3.13e-51: 182: 28.41		LIRA3_HUMAN (1-342): 1.66e-71: 234: 35.06
+	Hs
		798230 KI3L1_HUMAN (1-346): 5.84e-71: 229: 31.52		KI2S2_HUMAN (1-241): 9.82e-45: 159: 39.22
+	Hs
		252771 LIRA3_HUMAN (17-345): 3.4e-52: 180: 28.61		LIRA1_HUMAN (1-399): 1.17e-57: 198: 30.64
+	Hs
		47501 A0A8I5QEB2_HUMAN (1-330): 3.52e-69: 224: 33.93		KI2S5_HUMAN (1-241): 5.02e-42: 152: 36.47
+	Hs
		1141034 LIRB4_HUMAN (1-324): 1.6e-77: 246: 29.20		CD276_HUMAN (37-323): 1.43e-15: 80.6: 18.31