HitPredict

Interactor 1: GOSR1 (P38736)
Golgi SNAP receptor complex member 1 (Golgi SNARE protein 1) (Protein transport protein GOS1)
Gene: GOS1

Interactor 2: NYV1 (Q12255)
Vacuolar v-SNARE NYV1 (R-SNARE NYV1) (New v-SNARE 1) (Synaptobrevin NYV1)
Gene: NYV1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	24589832
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Synaptobrevin~V-SNARE_C
Common GO terms	GO:0005484 - SNAP receptor activity GO:0006886 - intracellular protein transport GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 223 Sc			1 253
+	Hs
		96844 E9PCW1_HUMAN (3-222): 5.27e-65: 203: 22.73		SC22B_HUMAN (47-253): 6.65e-42: 144: 14.49
+	Hs
		280077 GOSR1_HUMAN (3-222): 1.1e-64: 202: 22.54		SC22B_HUMAN (47-253): 6.65e-42: 144: 14.49
+	Sc
		646235 GOSR1_YEAST (1-223): 5.22e-59: 187: 100.00		SEC22_YEAST (35-253): 3.31e-45: 152: 16.82
+	At
		235609 VTI11_ARATH (17-206): 2.07e-55: 178: 18.33		VA711_ARATH (50-250): 6.85e-45: 151: 18.40
+	Mm
		312730 GOSR1_MOUSE (3-222): 1.03e-65: 205: 22.54		YKT6_MOUSE (92-221): 1.21e-30: 114: 20.00
+	Rn
		1204260 GOSR1_RAT (3-222): 1.89e-65: 204: 22.54		YKT6_RAT (92-221): 2.5e-30: 113: 19.26
+	Hs
		192156 GOSR1_HUMAN (3-222): 1.1e-64: 202: 22.54		YKT6_HUMAN (92-221): 3e-30: 113: 19.26
+	Hs
		331869 GOSR1_HUMAN (3-222): 1.1e-64: 202: 22.54		VAMP3_HUMAN (155-234): 2.96e-30: 110: 27.50
+	Dm
		1263458 GOSR1_DROME (5-222): 1.57e-49: 163: 21.40		Q7JYX5_DROME (49-247): 2.54e-43: 148: 19.05
+	Hs
		96843 E9PCW1_HUMAN (3-222): 5.27e-65: 203: 22.73		VAMP4_HUMAN (157-235): 7.41e-27: 102: 27.85
+	Hs
		278462 GOSR1_HUMAN (3-222): 1.1e-64: 202: 22.54		VAMP4_HUMAN (157-235): 7.41e-27: 102: 27.85
+	Hs
		280297 VTI1A_HUMAN (17-223): 5.45e-48: 158: 13.81		SC22B_HUMAN (47-253): 6.65e-42: 144: 14.49
+	Dm
		121813 GOSR1_DROME (5-222): 1.57e-49: 163: 21.40		M9PGI6_DROME (35-248): 4.76e-38: 134: 12.79
+	Dm
		305582 GOSR1_DROME (5-222): 1.57e-49: 163: 21.40		O77434_DROME (32-248): 2.78e-38: 134: 12.84
+	Dm
		614939 GOSR1_DROME (5-222): 1.57e-49: 163: 21.40		SYB_DROME (146-248): 1.41e-31: 115: 20.39
+	Dm
		1472282 GOSR1_DROME (5-222): 1.57e-49: 163: 21.40		Q9W3M8_DROME (92-221): 8.4e-28: 107: 17.78
+	Hs
		1154704 VTI1A_HUMAN (17-223): 5.45e-48: 158: 13.81		VAMP3_HUMAN (155-234): 2.96e-30: 110: 27.50
+	Rn
		1224615 VTI1A_RAT (17-223): 1.4e-46: 155: 13.15		VAMP1_RAT (161-251): 1.99e-28: 106: 26.37
+	Hs
		278542 VTI1A_HUMAN (17-223): 5.45e-48: 158: 13.81		VAMP4_HUMAN (157-235): 7.41e-27: 102: 27.85
+	Hs
		1383304 VTI1A_HUMAN (17-223): 5.45e-48: 158: 13.81		VAMP8_HUMAN (160-235): 1.45e-26: 101: 26.32