HitPredict

Interactor 1: TEM1 (P38987)
Protein TEM1
Gene: TEM1

Interactor 2: IQG1 (Q12280)
Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1)
Gene: IQG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.80	0.700

Property	Details
Experiments	9950677, 23966170
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Sc			1 1495
+	Hs
		1111447 RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14		IQGA2_HUMAN (88-1492): 0: 852: 15.36
+	Hs
		1145162 RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14		NGAP_HUMAN (827-1380): 2.09e-88: 315: 9.50
+	Hs
		976645 RB11A_HUMAN (10-227): 7e-78: 235: 18.72		NGAP_HUMAN (827-1380): 2.09e-88: 315: 9.50
+	Hs
		1144953 RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14		DAB2P_HUMAN (815-1259): 1.44e-73: 271: 9.78
+	Zm
		14476 B4FNJ6_MAIZE (16-219): 4.01e-79: 238: 19.51		A0A1D6G388_MAIZE (416-1342): 6.99e-76: 281: 9.57
+	Hs
		1135426 RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14		GAPD1_HUMAN (751-1282): 1e-67: 254: 11.73
+	Hs
		1145063 RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14		SYGP1_HUMAN (827-1224): 5.96e-68: 254: 12.26
+	Hs
		981344 RAB1A_HUMAN (10-217): 5.45e-83: 248: 21.05		SYGP1_HUMAN (827-1224): 5.96e-68: 254: 12.26
+	Mm
		104492 RAB1A_MOUSE (10-217): 5.45e-83: 248: 21.05		SYGP1_MOUSE (815-1224): 2.75e-66: 249: 13.10
+	At
		1441864 RABD1_ARATH (13-216): 1.06e-77: 234: 22.93		MYO6_ARATH (294-1030): 1.88e-69: 260: 11.08
+	Hs
		976494 RB11A_HUMAN (10-227): 7e-78: 235: 18.72		SYGP1_HUMAN (827-1224): 5.96e-68: 254: 12.26
+	Rn
		976726 RB11A_RAT (10-227): 7e-78: 235: 18.72		MYO5B_RAT (184-1030): 1.43e-67: 254: 9.81
+	Hs
		976283 RB11A_HUMAN (10-227): 7e-78: 235: 18.72		CNN3_HUMAN (90-366): 7.16e-64: 222: 15.04
+	Hs
		862852 RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14		IQGA1_HUMAN (88-1320): 3.63e-49: 194: 12.22
+	Hs
		976506 RB11A_HUMAN (10-227): 7e-78: 235: 18.72		CNN2_HUMAN (78-366): 1.66e-50: 183: 12.80
+	Hs
		901660 RAB7A_HUMAN (16-207): 1.17e-15: 74.7: 26.40		NGAP_HUMAN (827-1380): 2.09e-88: 315: 9.50
+	Dm
		197389 O18335_DROME (10-226): 1.64e-77: 234: 19.27		Q9VZI1_DROME (99-244): 9.06e-23: 99.1: 29.73
+	Hs
		901501 RAB7A_HUMAN (16-207): 1.17e-15: 74.7: 26.40		SYGP1_HUMAN (827-1224): 5.96e-68: 254: 12.26
+	Hs
		955920 RAB8A_HUMAN (13-216): 9.07e-79: 237: 20.00		TAGL_HUMAN (98-243): 5.13e-16: 80.3: 25.64
+	Hs
		790886 RB11A_HUMAN (10-227): 7e-78: 235: 18.72		TAGL2_HUMAN (106-243): 3.49e-13: 71.8: 17.57