HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.762

Property	Details
Experiments	28514442, 27432908, 28675297, 33961781, 22948661, 24366813, 25283809, 25796446, 27684187, 32292505, 26933062, 24255178, 25751139
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 1187
+	Hs
		125485 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		1076918 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		1076917 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		1087931 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Hs
		808660 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Hs
		1076872 MAGI3_HUMAN (69-270): 5.85e-40: 156: 21.64		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		1076909 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		1076894 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		1087910 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Dm
		1359218 SUDX_DROME (16-504): 4.46e-109: 347: 15.74		Q9V3V3_DROME (1-1187): 1.34e-173: 547: 24.75
+	Hs
		1336123 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		547209 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		546968 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		546967 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		808559 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		616920 MAGI3_HUMAN (69-270): 5.85e-40: 156: 21.64		PTPRB_HUMAN (597-1186): 2.37e-136: 459: 22.78
+	Hs
		299270 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		FARP2_HUMAN (14-523): 3.59e-140: 453: 21.60
+	Hs
		547208 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		1020213 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Rn
		94280 MAGI2_RAT (70-304): 4.04e-37: 148: 19.61		F1LXJ9_RAT (268-1183): 1.59e-68: 255: 12.60