Protein: SNX8
Sorting nexin-8

Gene: SNX8
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q9Y5X2

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0031901 - early endosome membrane
GO:0034498 - early endosome to Golgi transport
GO:0035091 - phosphatidylinositol binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1490485

AKT3
RAC-gamma serine/threonine-protein kinase

2

6

High-throughput

0.811

High

1380299

FBXW7
F-box/WD repeat-containing protein 7

4

3

Small-scale

0.691

High

596735

NCPR
NADPH--cytochrome P450 reductase

3

0

High-throughput

0.634

High

1112004

SNX1
Sorting nexin-1

1

18

Small-scale

0.618

High

1357706

SNX33
Sorting nexin-33

1

17

Small-scale

0.618

High

1401308

SNX18
Sorting nexin-18

1

16

Small-scale

0.618

High

1491760

SNX9
Sorting nexin-9

1

17

Small-scale

0.618

High

1491765

SNX8
Sorting nexin-8

1

15

Small-scale

0.618

High

1139311

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

5

High-throughput

0.606

High

1451261

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.580

High

881349

FAS
Fatty acid synthase

1

1

Small-scale

0.578

High

1393467

REEP6
Receptor expression-enhancing protein 6

2

3

High-throughput

0.553

High

1460203

PRAF1
Prenylated Rab acceptor protein 1

2

1

High-throughput

0.553

High

1214930

WLS
Protein wntless homolog

1

1

High-throughput

0.536

High

1403386

RUFY1
RUN and FYVE domain-containing protein 1

1

6

High-throughput

0.536

High

1413125

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

1

0

High-throughput

0.513

High

873172

RXRG
Retinoic acid receptor RXR-gamma

1

4

High-throughput

0.489

High

1160849

NFIL3
Nuclear factor interleukin-3-regulated protein

1

5

High-throughput

0.489

High

159936

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

6

High-throughput

0.479

High

243426

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

362426

ABL1
Tyrosine-protein kinase ABL1

1

14

High-throughput

0.479

High

401776

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.479

High

440807

FYN
Tyrosine-protein kinase Fyn

1

14

High-throughput

0.479

High

594153

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

699908

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

High-throughput

0.479

High

958058

RAB14
Ras-related protein Rab-14

1

13

High-throughput

0.479

High

988069

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

1367700

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1389862

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

4

Small-scale

0.479

High

1452440

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

14

High-throughput

0.479

High

1459476

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1278161

MAVS
Mitochondrial antiviral-signaling protein

1

3

Small-scale

0.470

High

326843

SPN1
Snurportin-1

1

0

High-throughput

0.458

High

248965

GSDME
Gasdermin-E

1

1

High-throughput

0.445

High

530672

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

583911

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

4

High-throughput

0.445

High

896480

ERF
ETS domain-containing transcription factor ERF

1

2

High-throughput

0.445

High

1239355

ARMC6
Armadillo repeat-containing protein 6

1

1

High-throughput

0.445

High

1325803

FXL16
F-box/LRR-repeat protein 16

1

2

High-throughput

0.445

High

72990

WDR64
WD repeat-containing protein 64

1

3

High-throughput

0.437

High

1100591

TIF1B
Transcription intermediary factor 1-beta

1

2

Small-scale

0.437

High

1256287

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

388344

GLPA
Glycophorin-A

1

0

High-throughput

0.426

High

1053091

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.426

High

1061570

ACTN3
Alpha-actinin-3

1

0

High-throughput

0.426

High

1433841

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.426

High

1460186

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.426

High

437845

HEPS
Serine protease hepsin

1

4

High-throughput

0.407

High

774734

BASI
Basigin

1

5

High-throughput

0.407

High

1057707

TNR9
Tumor necrosis factor receptor superfamily member 9

1

3

High-throughput

0.407

High

1366330

LPAR1
Lysophosphatidic acid receptor 1

1

6

High-throughput

0.407

High

1431304

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.407

High

1491766

NPTN
Neuroplastin

1

5

High-throughput

0.407

High

1308334

LACC1
Purine nucleoside phosphorylase LACC1

2

0

High-throughput

0.328

High

699479

PROP
Properdin

1

0

High-throughput

0.279

Low

833488

WNT5A
Protein Wnt-5a

1

0

High-throughput

0.279

Low

1410844

TMM47
Transmembrane protein 47

1

0

High-throughput

0.279

Low

1380339

MYDGF
Myeloid-derived growth factor

1

0

High-throughput

0.269

Low

418545

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

598800

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025