HitPredict

Interactor 1: GRIK1 (P39086)
Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5)
Gene: GRIK1

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12597860
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 918 Hs			1 1128
+	Hs
		1092408 GRIK2_HUMAN (6-913): 0: 861: 76.02		GRIP1_HUMAN (1-1128): 0: 656: 100.00
+	Hs
		838474 GRIA1_HUMAN (14-913): 0: 756: 37.41		GRIP1_HUMAN (1-1128): 0: 656: 100.00
+	Hs
		870113 GRIA4_HUMAN (20-918): 0: 746: 36.12		GRIP1_HUMAN (1-1128): 0: 656: 100.00
+	Hs
		838540 GRIA3_HUMAN (1-904): 0: 739: 36.21		GRIP1_HUMAN (1-1128): 0: 656: 100.00
+	Rn
		623655 GRIA1_RAT (14-913): 0: 749: 37.15		GRIP1_RAT (1-1128): 0: 624: 93.53
+	Rn
		623721 GRIA4_RAT (20-918): 0: 746: 36.12		GRIP1_RAT (1-1128): 0: 624: 93.53
+	Hs
		811286 GRIK1_HUMAN (1-918): 0: 935: 100.00		DLG4_HUMAN (1011-1125): 1.86e-15: 83.5: 23.58
+	Hs
		1006057 GRIK2_HUMAN (6-913): 0: 861: 76.02		DLG4_HUMAN (1011-1125): 1.86e-15: 83.5: 23.58
+	Rn
		723862 GRIK2_RAT (12-913): 0: 858: 76.19		DLG4_RAT (1011-1125): 1.77e-15: 83.5: 23.58
+	Mm
		811304 GRIK2_MOUSE (12-913): 0: 858: 76.19		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Hs
		1091485 GRIK2_HUMAN (6-913): 0: 861: 76.02		DLG1_HUMAN (945-1095): 3.58e-14: 79.7: 15.13
+	Hs
		1092405 GRIK2_HUMAN (6-913): 0: 861: 76.02		DLG3_HUMAN (874-1094): 9.36e-13: 74.7: 16.67
+	Hs
		838451 GRIA1_HUMAN (14-913): 0: 756: 37.41		DLG1_HUMAN (945-1095): 3.58e-14: 79.7: 15.13
+	Mm
		663045 GRIA1_MOUSE (14-913): 0: 747: 37.15		DLG2_MOUSE (1011-1128): 3.03e-16: 86.2: 17.60
+	Rn
		623648 GRIA1_RAT (14-913): 0: 749: 37.15		DLG4_RAT (1011-1125): 1.77e-15: 83.5: 23.58
+	Mm
		1223787 GRIA4_MOUSE (20-918): 0: 748: 36.12		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Mm
		663032 GRIA1_MOUSE (14-913): 0: 747: 37.15		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Rn
		623661 GRIA1_RAT (14-913): 0: 749: 37.15		DLG1_RAT (954-1095): 1.31e-13: 77.7: 16.08
+	Mm
		663021 GRIA1_MOUSE (14-913): 0: 747: 37.15		DLG3_MOUSE (866-1094): 1.6e-13: 77.3: 14.35
+	Hs
		838524 GRIA3_HUMAN (1-904): 0: 739: 36.21		DLG4_HUMAN (1011-1125): 1.86e-15: 83.5: 23.58