HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21280222, 34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 378
+	Hs
		818337 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MSI2H_HUMAN (18-364): 1.61e-57: 192: 29.97
+	Mm
		818711 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		HNRPD_MOUSE (8-299): 1.73e-54: 184: 34.59
+	Hs
		162023 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30
+	Hs
		609753 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27
+	Mm
		291907 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		ROA2_MOUSE (8-126): 3.48e-26: 109: 29.27
+	Hs
		852025 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00
+	Hs
		818011 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PABP4_HUMAN (6-339): 1.18e-16: 83.6: 13.82
+	Hs
		996662 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59
+	Hs
		818002 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		ROA0_HUMAN (17-115): 5.36e-10: 62: 34.34
+	Dm
		1098043 DICH_DROME (41-117): 1.19e-33: 129: 88.31		Q9VBQ1_DROME (119-239): 7.29e-25: 107: 26.45
+	Hs
		609821 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27
+	Hs
		453311 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20
+	Hs
		996644 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		ROA0_HUMAN (17-115): 5.36e-10: 62: 34.34