HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: SPB8 (P50452)
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)
Gene: SERPINB8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 374
+	Hs
		397016 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PAI2_HUMAN (1-374): 4.69e-159: 454: 42.79
+	Hs
		675627 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		ILEU_HUMAN (1-374): 1.27e-159: 454: 51.72
+	Hs
		818577 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPB13_HUMAN (1-374): 2.59e-155: 443: 39.03
+	Hs
		818366 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPB12_HUMAN (1-374): 8.9e-145: 417: 39.51
+	Hs
		271857 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPB7_HUMAN (1-374): 1.65e-144: 416: 36.36
+	Hs
		344108 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		ANT3_HUMAN (3-374): 1.73e-143: 416: 37.34
+	Hs
		738732 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPB5_HUMAN (1-374): 8.53e-141: 406: 37.73
+	Hs
		344176 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		A1AT_HUMAN (2-374): 1.43e-139: 404: 31.75
+	Hs
		397097 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PAI1_HUMAN (4-374): 1.29e-133: 389: 30.50
+	Hs
		668017 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		SPB3_HUMAN (1-374): 7.84e-152: 435: 43.62
+	Hs
		331682 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		AACT_HUMAN (4-374): 7.5e-141: 408: 33.25
+	Hs
		331681 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		A1AT_HUMAN (2-374): 1.43e-139: 404: 31.75
+	Hs
		818224 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPA12_HUMAN (3-374): 4.99e-52: 180: 29.71