Interactor 1: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 37968396, 16554755, 31848235
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB_C~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 437
Sc

1 437
+ At
+ At
+ Hs
+ Dm
+ Hs
+ Rn
+ Hs
+ Dm
+ At
+ Hs
+ Dm
+ Dm
+ At
+ Sc
+ Sc
+ Dm
+ Sc
+ Hs
+ At
+ Dm

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Last updated: 11Aug2025