Interactor 1: SKI (P49140)
Ski oncogene (Proto-oncogene c-Ski)
Gene: SKI

Interactor 2: SMAD3 (P84023)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3)
Gene: SMAD3

Species: Gallus gallus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22461172
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MH2~c-SKI_SMAD_bind
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
GO:0005737 - cytoplasm
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 750
Gg

1 426
+ Gg
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+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
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+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024