HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: M3KSL (Q95UN8)
Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase) (Protein slipper) (dMLK)
Gene: slpr

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.850

The method score is based on:

Property Details
Experiments 20736302, 20404112, 15710747
Identification Methods affinity chromatography technology, two hybrid, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0007254 - JNK cascade
GO:0007391 - dorsal closure
GO:0007394 - dorsal closure, elongation of leading edge cells
GO:0046330 - positive regulation of JNK cascade
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Dm

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Service provided by Combinatics, Japan

Last updated: 11Aug2025