Interactor 1: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB
Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.55 | 0.726 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27106262, 29269425, 12646252, 31451549, 18172499, 22337874, 28223335, 31533005, 35044719, 16678796, 23252402 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study, unspecified method, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
