Protein: HBP1
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)

Gene: HBP1
Organism: Homo sapiens
Interactions: 122
UniProt ID: O60381

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

248320

ARMC8
Armadillo repeat-containing protein 8

2

7

High-throughput

0.789

High

248351

RMD5A
E3 ubiquitin-protein transferase RMND5A

3

9

High-throughput

0.656

High

248362

GID8
Glucose-induced degradation protein 8 homolog

3

11

High-throughput

0.650

High

248337

SIN3A
Paired amphipathic helix protein Sin3a

2

7

Small-scale

0.644

High

248265

RB
Retinoblastoma-associated protein

2

3

Small-scale

0.631

High

248256

HBP1
HMG box-containing protein 1

1

17

High-throughput

0.618

High

248356

TF7L2
Transcription factor 7-like 2

1

17

Small-scale

0.618

High

248349

WDR26
WD repeat-containing protein 26

2

20

Small-scale

0.595

High

248293

HDAC1
Histone deacetylase 1

2

20

Small-scale

0.584

High

248290

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.561

High

248331

CBP
CREB-binding protein

1

20

Small-scale

0.561

High

248262

MYC
Myc proto-oncogene protein

1

15

Small-scale

0.552

High

248263

ESR1
Estrogen receptor

1

19

High-throughput

0.541

High

248285

EWS
RNA-binding protein EWS

1

13

High-throughput

0.541

High

248298

CASP8
Caspase-8

1

2

High-throughput

0.541

High

248343

ANKR2
Ankyrin repeat domain-containing protein 2

1

8

High-throughput

0.541

High

248301

SMAD1
Mothers against decapentaplegic homolog 1

1

20

High-throughput

0.508

High

248364

ZN212
Zinc finger protein 212

1

7

Small-scale

0.508

High

248280

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.501

High

248326

RBCC1
RB1-inducible coiled-coil protein 1

1

7

High-throughput

0.494

High

248272

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

2

High-throughput

0.489

High

248289

RBL2
Retinoblastoma-like protein 2

1

3

Small-scale

0.481

High

130319

SPT5H
Transcription elongation factor SPT5

1

16

High-throughput

0.479

High

160027

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

20

High-throughput

0.479

High

182868

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.479

High

248257

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

4

High-throughput

0.479

High

248259

H2AY
Core histone macro-H2A.1

1

11

High-throughput

0.479

High

248260

SAP30
Histone deacetylase complex subunit SAP30

1

3

High-throughput

0.479

High

248261

RL1D1
Ribosomal L1 domain-containing protein 1

1

4

High-throughput

0.479

High

248266

TOP2A
DNA topoisomerase 2-alpha

1

2

High-throughput

0.479

High

248267

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.479

High

248268

EGR1
Early growth response protein 1

1

14

High-throughput

0.479

High

248269

SON
Protein SON

1

9

High-throughput

0.479

High

248270

TBG1
Tubulin gamma-1 chain

1

7

High-throughput

0.479

High

248271

ARI4A
AT-rich interactive domain-containing protein 4A

1

20

High-throughput

0.479

High

248273

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.479

High

248274

RBM34
RNA-binding protein 34

1

12

High-throughput

0.479

High

248275

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.479

High

248276

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

248277

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.479

High

248279

BRPF1
Peregrin

1

10

High-throughput

0.479

High

248281

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.479

High

248282

RAN
GTP-binding nuclear protein Ran

1

7

High-throughput

0.479

High

248283

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

248284

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

248286

TOP2B
DNA topoisomerase 2-beta

1

10

High-throughput

0.479

High

248287

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.479

High

248288

SRSF4
Serine/arginine-rich splicing factor 4

1

10

High-throughput

0.479

High

248291

TRI26
Tripartite motif-containing protein 26

1

5

High-throughput

0.479

High

248292

PABP4
Polyadenylate-binding protein 4

1

3

High-throughput

0.479

High

248294

PWP1
Periodic tryptophan protein 1 homolog

1

20

High-throughput

0.479

High

248295

CUL4A
Cullin-4A

1

15

High-throughput

0.479

High

248296

CUL4B
Cullin-4B

1

15

High-throughput

0.479

High

248297

NOG2
Nucleolar GTP-binding protein 2

1

4

High-throughput

0.479

High

248299

PUM3
Pumilio homolog 3

1

2

High-throughput

0.479

High

248300

SKI2
Superkiller complex protein 2

1

11

High-throughput

0.479

High

248302

RBBP7
Histone-binding protein RBBP7

1

19

High-throughput

0.479

High

248305

ZN800
Zinc finger protein 800

1

3

High-throughput

0.479

High

248306

GLYR1
Cytokine-like nuclear factor N-PAC

1

5

High-throughput

0.479

High

248307

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

248308

RRP12
RRP12-like protein

1

1

High-throughput

0.479

High

248309

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

10

High-throughput

0.479

High

248310

HP1B3
Heterochromatin protein 1-binding protein 3

1

2

High-throughput

0.479

High

248311

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

1

High-throughput

0.479

High

248313

DHX57
Putative ATP-dependent RNA helicase DHX57

1

14

High-throughput

0.479

High

248314

LARP1
La-related protein 1

1

8

High-throughput

0.479

High

248315

RBP10
Ran-binding protein 10

1

14

High-throughput

0.479

High

248316

LARP4
La-related protein 4

1

7

High-throughput

0.479

High

248317

DHX30
ATP-dependent RNA helicase DHX30

1

12

High-throughput

0.479

High

248318

MAEA
E3 ubiquitin-protein transferase MAEA

1

11

High-throughput

0.479

High

248322

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

5

High-throughput

0.479

High

248323

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

248324

DDX54
ATP-dependent RNA helicase DDX54

1

12

High-throughput

0.479

High

248325

BRX1
Ribosome biogenesis protein BRX1 homolog

1

5

High-throughput

0.479

High

248327

PHIP
PH-interacting protein

1

20

High-throughput

0.479

High

248328

SRS12
Serine/arginine-rich splicing factor 12

1

7

High-throughput

0.479

High

248330

LAR4B
La-related protein 4B

1

7

High-throughput

0.479

High

248332

RENT1
Regulator of nonsense transcripts 1

1

4

High-throughput

0.479

High

248334

AURKB
Aurora kinase B

1

15

High-throughput

0.479

High

248335

DDX27
Probable ATP-dependent RNA helicase DDX27

1

11

High-throughput

0.479

High

248336

RANB9
Ran-binding protein 9

1

14

High-throughput

0.479

High

248338

EBP2
Probable rRNA-processing protein EBP2

1

2

High-throughput

0.479

High

248339

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.479

High

248340

CHOLN
Protein cholesin

1

3

High-throughput

0.479

High

248341

RIOK2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.479

High

248342

GTPB4
GTP-binding protein 4

1

7

High-throughput

0.479

High

248344

SP130
Histone deacetylase complex subunit SAP130

1

16

High-throughput

0.479

High

248345

ING2
Inhibitor of growth protein 2

1

17

High-throughput

0.479

High

248346

SENP3
Sentrin-specific protease 3

1

3

High-throughput

0.479

High

248347

NOL6
Nucleolar protein 6

1

1

High-throughput

0.479

High

248348

RIOX1
Ribosomal oxygenase 1

1

1

High-throughput

0.479

High

248350

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

10

High-throughput

0.479

High

248352

SP30L
Histone deacetylase complex subunit SAP30L

1

3

High-throughput

0.479

High

248353

BRMS1
Breast cancer metastasis-suppressor 1

1

10

High-throughput

0.479

High

248354

SHCAF
SIN3-HDAC complex-associated factor

1

2

High-throughput

0.479

High

248355

SSF1
Suppressor of SWI4 1 homolog

1

2

High-throughput

0.479

High

248357

INCE
Inner centromere protein

1

5

High-throughput

0.479

High

248358

PNO1
RNA-binding protein PNO1

1

1

High-throughput

0.479

High

248359

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

1

High-throughput

0.479

High

248360

SDA1
Protein SDA1 homolog

1

1

High-throughput

0.479

High

248363

TEX10
Testis-expressed protein 10

1

1

High-throughput

0.479

High

248365

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

High-throughput

0.479

High

248366

HERC5
E3 ISG15--protein ligase HERC5

1

7

High-throughput

0.479

High

248367

FBW1B
F-box/WD repeat-containing protein 11

1

14

High-throughput

0.479

High

248368

MRT4
mRNA turnover protein 4 homolog

1

6

High-throughput

0.479

High

248369

MKLN1
Muskelin

1

7

High-throughput

0.479

High

248371

NOP58
Nucleolar protein 58

1

5

High-throughput

0.479

High

248258

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.458

High

248264

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.458

High

248303

SMN
Survival motor neuron protein

1

0

High-throughput

0.458

High

248370

NOB1
RNA-binding protein NOB1

1

0

High-throughput

0.458

High

248372

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

High-throughput

0.458

High

248278

MAP1B
Microtubule-associated protein 1B

1

20

High-throughput

0.437

High

248312

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.437

High

248361

PK1IP
p21-activated protein kinase-interacting protein 1

1

12

High-throughput

0.437

High

248333

KBP
KIF-binding protein

1

0

High-throughput

0.282

High

248373

CD2AP
CD2-associated protein

1

0

High-throughput

0.265

Low

248329

CCGL
Voltage-dependent calcium channel gamma-like subunit

1

0

High-throughput

0.251

Low

248304

QPCT
Glutaminyl-peptide cyclotransferase

1

0

High-throughput

0.249

Low

248319

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.249

Low

248321

GID4
Glucose-induced degradation protein 4 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025