HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.50	0.627

Property	Details
Experiments	33961781, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 499 Hs			1 247
+	Hs
		833704 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		833868 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		834015 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		834014 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		834024 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		625306 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		625296 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		625383 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		909447 CDK3_HUMAN (160-495): 1.29e-125: 370: 24.20		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		683206 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646727 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683207 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		834018 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646728 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		625334 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683907 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		625130 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683268 CDK3_HUMAN (160-495): 1.29e-125: 370: 24.20		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646799 CDK3_HUMAN (160-495): 1.29e-125: 370: 24.20		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683964 CDK3_HUMAN (160-495): 1.29e-125: 370: 24.20		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16