HitPredict

Interactor 1: CRY1 (P97784)
Cryptochrome-1
Gene: CRY1

Interactor 2: KC1E (Q9JMK2)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: Csnk1e

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	21966515, 23555304
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0007623 - circadian rhythm GO:0032922 - circadian regulation of gene expression and 1 others more... GO:0042752 - regulation of circadian rhythm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 606 Mm			1 416
+	Mm
		956904 CRY1_MOUSE (1-606): 0: 895: 100.00		KC1A_MOUSE (2-327): 2.56e-121: 357: 69.02
+	Hs
		830368 CRY1_HUMAN (1-606): 0: 806: 92.41		KC1E_HUMAN (1-416): 6.6e-136: 397: 98.80
+	Hs
		822272 CRY1_HUMAN (1-606): 0: 806: 92.41		KC1D_HUMAN (1-406): 3.49e-124: 367: 82.27
+	Hs
		830380 CRY2_HUMAN (3-505): 0: 674: 80.32		KC1E_HUMAN (1-416): 6.6e-136: 397: 98.80
+	Hs
		822280 CRY2_HUMAN (3-505): 0: 674: 80.32		KC1D_HUMAN (1-406): 3.49e-124: 367: 82.27
+	Mm
		1206798 CRY2_MOUSE (2-505): 0: 678: 80.36		KC1A_MOUSE (2-327): 2.56e-121: 357: 69.02
+	At
		1275559 CRY2_ARATH (1-489): 0: 546: 25.45		CKL3_ARATH (1-395): 1.12e-127: 376: 52.02
+	At
		1228208 CRY2_ARATH (1-489): 0: 546: 25.45		CKL4_ARATH (1-405): 2.79e-127: 375: 51.36