HitPredict

Interactor 1: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	36779422, 36736316
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~SAM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 1011
+	Hs
		835862 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		835475 GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00		ANS1A_HUMAN (502-904): 1.42e-45: 180: 15.23
+	Dm
		576751 SGG_DROME (68-456): 1.03e-137: 408: 73.15		Q9VU88_DROME (388-928): 2.17e-53: 200: 32.05
+	Hs
		835913 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		ANS1A_HUMAN (502-904): 1.42e-45: 180: 15.23
+	Hs
		625176 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		724714 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		625177 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Hs
		528401 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MYH8_HUMAN (2-529): 9.87e-20: 97.6: 9.65
+	Hs
		960128 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH2_HUMAN (16-806): 8.98e-26: 117: 8.00
+	Hs
		528368 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH6_HUMAN (2-794): 8.99e-25: 114: 9.50
+	Hs
		835352 GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Hs
		522542 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH1_HUMAN (185-793): 7.46e-20: 98: 9.05
+	Hs
		528405 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH8_HUMAN (2-529): 9.87e-20: 97.6: 9.65
+	Hs
		835712 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Hs
		522604 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH7_HUMAN (4-426): 2.63e-13: 76.8: 10.58
+	Dm
		576667 SGG_DROME (68-456): 1.03e-137: 408: 73.15		Q9VM93_DROME (56-568): 1.18e-10: 68.1: 7.13
+	Hs
		960129 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH13_HUMAN (1-409): 8.9e-13: 74.9: 9.76
+	Hs
		502908 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH3_HUMAN (18-342): 1.75e-11: 70.7: 7.69
+	Dr
		71537 Q7T3L7_DANRE (116-418): 8.95e-134: 390: 31.19		B3DKC5_DANRE (84-341): 3.17e-11: 69.2: 17.04