Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B
Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.78 | 1.00 | 0.887 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 29568061, 36779422, unassigned1655 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC37_M~Pkinase, CDC37_N~Pkinase |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
