HitPredict

Interactor 1: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Interactor 2: SPRE1 (Q7Z699)
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1)
Gene: SPRED1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0090051 - negative regulation of cell migration involved in sprouting angiogenesis
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 444
+	Hs
		1151093 Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		453057 HXB7_HUMAN (69-256): 1.01e-34: 127: 29.02		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		837817 MEOX1_HUMAN (4-270): 1.53e-28: 111: 36.73		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		446904 HXC4_HUMAN (186-244): 1.32e-13: 71.2: 61.02		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		838087 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		Q7Z783_HUMAN (169-433): 7.64e-65: 213: 16.61
+	Hs
		208107 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		SPY2_HUMAN (169-433): 5.08e-63: 208: 16.61
+	Hs
		208331 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		208375 Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		208414 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79
+	Hs
		208426 Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79
+	Hs
		447297 HXB5_HUMAN (108-262): 1.13e-35: 131: 32.75		HOME3_HUMAN (11-333): 1.13e-50: 177: 11.68
+	Hs
		837852 MEOX1_HUMAN (4-270): 1.53e-28: 111: 36.73		HOME3_HUMAN (11-333): 1.13e-50: 177: 11.68
+	Hs
		538731 HXB2_HUMAN (188-244): 9.11e-14: 72.8: 68.42		HOME1_HUMAN (11-343): 1.82e-65: 215: 12.89
+	Hs
		538744 HXB2_HUMAN (188-244): 9.11e-14: 72.8: 68.42		HOME2_HUMAN (11-230): 3.06e-59: 199: 12.11