HitPredict

Interactor 1: CRIP1 (P50238)
Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP)
Gene: CRIP1

Interactor 2: SH2D3 (Q8N5H7)
SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1)
Gene: SH2D3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 77 Hs			1 860
+	Hs
		1234547 PDLI5_HUMAN (4-61): 4.27e-15: 69.8: 23.73		SH2D3_HUMAN (23-860): 0: 862: 100.00
+	Hs
		412099 LIMK1_HUMAN (1-68): 2.45e-22: 90.2: 26.47		FYN_HUMAN (82-423): 9e-64: 225: 10.99
+	Hs
		433500 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		YES_HUMAN (81-393): 4.07e-61: 218: 11.78
+	Hs
		433354 LASP1_HUMAN (2-61): 1.03e-21: 86.3: 41.67		YES_HUMAN (81-393): 4.07e-61: 218: 11.78
+	Hs
		523077 MICA1_HUMAN (4-55): 7.68e-19: 80.4: 35.19		SRC_HUMAN (20-393): 2.03e-60: 216: 12.76
+	Hs
		561402 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		FER_HUMAN (86-569): 1.39e-54: 205: 14.90
+	Hs
		254384 LDB3_HUMAN (3-57): 8.54e-16: 71.7: 25.00		SRC_HUMAN (20-393): 2.03e-60: 216: 12.76
+	Hs
		434057 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		LYN_HUMAN (132-424): 2.93e-54: 198: 11.39
+	Hs
		433853 MICA3_HUMAN (2-56): 5.21e-21: 86.4: 40.35		LYN_HUMAN (132-424): 2.93e-54: 198: 11.39
+	Hs
		111447 PDLI7_HUMAN (3-58): 2.48e-13: 64.8: 22.81		J3QRU1_HUMAN (81-393): 4.61e-61: 218: 11.78
+	Hs
		433484 PDLI7_HUMAN (3-58): 2.48e-13: 64.8: 22.81		YES_HUMAN (81-393): 4.07e-61: 218: 11.78
+	Hs
		802603 LASP1_HUMAN (2-61): 1.03e-21: 86.3: 41.67		CRK_HUMAN (209-512): 9.59e-54: 190: 16.06
+	Hs
		802673 MICA1_HUMAN (4-55): 7.68e-19: 80.4: 35.19		CRK_HUMAN (209-512): 9.59e-54: 190: 16.06
+	Gg
		823525 PAXI_CHICK (4-61): 4.97e-14: 66.7: 32.76		CRK_CHICK (219-480): 8.82e-53: 188: 15.97
+	Rn
		1137277 PAXI_RAT (4-61): 4.84e-13: 64: 31.03		CRKL_RAT (220-480): 1.55e-51: 184: 18.47
+	Hs
		924925 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		924720 MICA1_HUMAN (4-55): 7.68e-19: 80.4: 35.19		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		597760 CSRP1_HUMAN (3-69): 1.27e-18: 76.9: 44.78		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		209124 MICA1_HUMAN (4-55): 7.68e-19: 80.4: 35.19		NCK2_HUMAN (98-309): 6.4e-23: 103: 18.72
+	Hs
		924889 PDLI7_HUMAN (3-58): 2.48e-13: 64.8: 22.81		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00