Interactor 1: MMP14 (P50281)
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)
Gene: MMP14

Interactor 2: DEF1 (P59665)
Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Gene: DEFA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 19181662
Identification Methods protease assay
Interaction Type cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005796 - Golgi lumen
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 582
Hs

1 94
+ Hs

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Last updated: 15 Jul 2024