Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) (Tyrosine-protein kinase mTOR) (EC 2.7.10.2)
Gene: MTOR
Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) (Tyrosine-protein kinase mTOR) (EC 2.7.10.2)
Gene: MTOR
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.93 | 1.00 | 0.967 |
The method score is based on:
Property | Details |
---|---|
Experiments | 18030348, 16870609, 17360675, 19299511, 34171383, 11114166, 9334222, 19225151, 24670654, 11438723 |
Identification Methods | enzymatic study, affinity chromatography technology, in-gel kinase assay, anti tag coimmunoprecipitation, protein kinase assay, beta lactamase complementation |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | FAT~FAT, FAT~FATC, FAT~mTOR_dom, FAT~PI3_PI4_kinase, FATC~PI3_PI4_kinase, FRB_dom~FRB_dom, FRB_dom~PI3_PI4_kinase, PI3_PI4_kinase~mTOR_dom, PI3_PI4_kinase~PI3_PI4_kinase |
Common GO terms | GO:0000139 - Golgi membrane GO:0000822 - inositol hexakisphosphate binding GO:0001002 - RNA polymerase III type 1 promoter sequence-specific DNA binding GO:0001003 - RNA polymerase III type 2 promoter sequence-specific DNA binding GO:0001006 - RNA polymerase III type 3 promoter sequence-specific DNA binding and 111 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 11Aug2025