Interactor 1: DAF4 (P50488)
Cell surface receptor daf-4 (EC 2.7.11.30) (Abnormal dauer formation protein 4)
Gene: daf-4

Interactor 2: HSP90 (Q18688)
Heat shock protein 90 (Abnormal dauer formation protein 21)
Gene: daf-21

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.43 1.00 0.656

The method score is based on:

Property Details
Experiments 14992718
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0002119 - nematode larval development
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0008340 - determination of adult lifespan
GO:0040024 - dauer larval development
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 744
Ce

1 702
+ Hs
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+ Ce
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Last updated: 15 Jul 2024