HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24855949
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 216
+	Hs
		1091402 ANK3_HUMAN (3-153): 3.24e-36: 133: 16.94		RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47
+	Hs
		1145176 ANR26_HUMAN (3-155): 9.54e-35: 129: 18.71		RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47
+	Hs
		976668 ANR26_HUMAN (3-155): 9.54e-35: 129: 18.71		RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67
+	Hs
		1145101 TANC1_HUMAN (56-154): 1.19e-14: 71.9: 21.00		RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47
+	Hs
		1145166 KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48		RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47
+	Hs
		1145141 RAI14_HUMAN (1-64): 1e-11: 63.4: 21.21		RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47
+	Hs
		332396 TNKS1_HUMAN (49-142): 1.95e-13: 68.6: 25.26		RAN_HUMAN (1-216): 1.48e-79: 238: 100.00
+	Hs
		920420 DAPK1_HUMAN (69-155): 1.65e-14: 71.5: 24.14		RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67
+	Hs
		976655 KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48		RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67
+	Hs
		976621 RAI14_HUMAN (1-64): 1e-11: 63.4: 21.21		RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67
+	Hs
		901673 ANR50_HUMAN (26-148): 7.13e-27: 106: 27.64		RAB7A_HUMAN (8-166): 7.47e-29: 108: 33.13
+	Hs
		901500 ANR27_HUMAN (2-85): 1.33e-16: 77.7: 21.59		RAB7A_HUMAN (8-166): 7.47e-29: 108: 33.13
+	Hs
		630939 ANR27_HUMAN (2-85): 1.33e-16: 77.7: 21.59		RAB4A_HUMAN (11-169): 1.54e-27: 105: 34.57
+	Hs
		295473 PSD10_HUMAN (1-85): 4.42e-13: 65.7: 22.73		RAB7A_HUMAN (8-166): 7.47e-29: 108: 33.13
+	Hs
		901672 KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48		RAB7A_HUMAN (8-166): 7.47e-29: 108: 33.13
+	Hs
		901631 RAI14_HUMAN (1-64): 1e-11: 63.4: 21.21		RAB7A_HUMAN (8-166): 7.47e-29: 108: 33.13
+	Hs
		631017 KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48		RAB4A_HUMAN (11-169): 1.54e-27: 105: 34.57