Protein: ANR27
Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein)

Gene: ANR27, ANKRD27
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q96NW4

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005764 - lysosome
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1399269

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

12

High-throughput

0.871

High

683506

IKBA
NF-kappa-B inhibitor alpha

3

19

High-throughput

0.861

High

1399272

RAB21
Ras-related protein Rab-21

2

9

High-throughput

0.789

High

1399270

VPS29
Vacuolar protein sorting-associated protein 29

4

1

High-throughput

0.697

High

1151624

TRIP6
Thyroid receptor-interacting protein 6

1

5

High-throughput

0.691

High

1087026

KIF5A
Kinesin heavy chain isoform 5A

1

4

Small-scale

0.683

High

1399266

VPS35
Vacuolar protein sorting-associated protein 35

4

1

Small-scale

0.673

High

1340738

TPC2
Two pore channel protein 2

2

6

High-throughput

0.628

High

1086744

RB40B
Ras-related protein Rab-40B

1

9

Small-scale

0.621

High

1360869

RB40A
Ras-related protein Rab-40A

1

10

Small-scale

0.621

High

1399267

RB40C
Ras-related protein Rab-40C

1

10

Small-scale

0.621

High

414434

P53
Cellular tumor antigen p53

1

2

High-throughput

0.618

High

630939

RAB4A
Ras-related protein Rab-4A

1

4

High-throughput

0.618

High

901500

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.618

High

902014

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.618

High

1114046

CUL3
Cullin-3

1

8

High-throughput

0.618

High

1010092

DLK1
Protein delta homolog 1

2

8

High-throughput

0.611

High

157747

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.586

High

443480

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.586

High

1385013

ZN669
Zinc finger protein 669

2

3

High-throughput

0.574

High

908043

VAMP7
Vesicle-associated membrane protein 7

1

0

Small-scale

0.554

High

244183

KIF5C
Kinesin heavy chain isoform 5C

1

4

Small-scale

0.553

High

281776

VP26A
Vacuolar protein sorting-associated protein 26A

1

1

High-throughput

0.536

High

971894

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.536

High

990619

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1066450

RBBP4
Histone-binding protein RBBP4

1

1

High-throughput

0.536

High

1104648

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.536

High

1153784

NCOA1
Nuclear receptor coactivator 1

1

3

High-throughput

0.536

High

1194110

VP26B
Vacuolar protein sorting-associated protein 26B

1

1

High-throughput

0.536

High

1383814

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

247156

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.513

High

1153993

SMAD1
Mothers against decapentaplegic homolog 1

1

4

High-throughput

0.508

High

1105651

GOGA4
Golgin subfamily A member 4

1

11

Small-scale

0.506

High

1061104

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.489

High

218645

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

1049679

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1178317

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1276278

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1367055

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1396769

SNX27
Sorting nexin-27

1

11

High-throughput

0.479

High

1399268

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1399273

EPN1
Epsin-1

1

3

High-throughput

0.479

High

1233425

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1239034

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.445

High

1310925

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

5

High-throughput

0.445

High

1399044

TMM74
Transmembrane protein 74

1

1

High-throughput

0.445

High

1399271

SL9A2
Sodium/hydrogen exchanger 2

1

3

High-throughput

0.445

High

372880

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.437

High

879373

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

47916

S12A8
Solute carrier family 12 member 8

1

0

High-throughput

0.426

High

1155092

UT2
Urea transporter 2

1

0

High-throughput

0.426

High

1208131

S35D3
Solute carrier family 35 member D3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025