HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31046837, unassigned1853
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 548 Hs			1 2527
+	Hs
		1121648 Q53HV2_HUMAN (9-538): 0: 561: 26.39		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		826696 TCPG_HUMAN (10-547): 0: 558: 28.21		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130804 V9HW37_HUMAN (2-524): 0: 535: 29.62		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		821249 TCPE_HUMAN (2-524): 0: 535: 29.62		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		843234 TCPD_HUMAN (19-525): 0: 530: 28.24		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		573297 TCPA_HUMAN (21-541): 0: 528: 29.89		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		842889 TCPQ_HUMAN (1-548): 0: 616: 100.00		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		1105482 TCPH_HUMAN (9-538): 0: 564: 26.39		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		826684 TCPG_HUMAN (10-547): 0: 558: 28.21		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		821234 TCPE_HUMAN (2-524): 0: 535: 29.62		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		843220 TCPD_HUMAN (19-525): 0: 530: 28.24		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		573283 TCPA_HUMAN (21-541): 0: 528: 29.89		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38