HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 673 Hs			1 2896
+	Mm
		1111986 FXR1_MOUSE (14-673): 0: 981: 62.83		PRC2C_MOUSE (1-2896): 0: 713: 83.24
+	Hs
		843980 FXR1_HUMAN (14-673): 0: 798: 51.34		PRC2C_HUMAN (1-2896): 0: 771: 100.00
+	Mm
		1111989 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		PRC2C_MOUSE (1-2896): 0: 713: 83.24
+	Hs
		820852 FXR2_HUMAN (1-673): 0: 1004: 100.00		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		844097 FXR2_HUMAN (1-673): 0: 1004: 100.00		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Mm
		1142920 FXR1_MOUSE (14-673): 0: 981: 62.83		ITSN1_MOUSE (494-1149): 6.87e-10: 67.3: 11.15
+	Mm
		1142913 FXR1_MOUSE (14-673): 0: 981: 62.83		NCOR2_MOUSE (1109-2884): 1.02e-09: 66.7: 8.66
+	Mm
		1142853 FXR1_MOUSE (14-673): 0: 981: 62.83		PRC2A_MOUSE (2007-2896): 2.45e-09: 65.6: 8.30
+	Mm
		1142852 FXR1_MOUSE (14-673): 0: 981: 62.83		PRC2B_MOUSE (1566-2896): 4.65e-09: 64.4: 7.39
+	Hs
		311796 FXR1_HUMAN (14-673): 0: 798: 51.34		TACC2_HUMAN (62-2285): 2.28e-23: 111: 9.24
+	Hs
		820851 FXR1_HUMAN (14-673): 0: 798: 51.34		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Mm
		729462 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		PRC2C_MOUSE (1-2896): 0: 713: 83.24
+	Hs
		843719 FXR1_HUMAN (14-673): 0: 798: 51.34		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Mm
		292197 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		BSN_MOUSE (29-1686): 3.93e-18: 94.8: 8.16
+	Mm
		1207085 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		ANR17_MOUSE (1566-2453): 3.47e-14: 81.6: 15.34
+	Mm
		1207112 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		NCOR2_MOUSE (1109-2884): 1.02e-09: 66.7: 8.66
+	Mm
		1186751 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		PRC2A_MOUSE (2007-2896): 2.45e-09: 65.6: 8.30
+	Mm
		1186627 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		PRC2B_MOUSE (1566-2896): 4.65e-09: 64.4: 7.39
+	Mm
		292190 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		BSN_MOUSE (29-1686): 3.93e-18: 94.8: 8.16
+	Mm
		729531 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		PRC2B_MOUSE (1566-2896): 4.65e-09: 64.4: 7.39