HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: TBC17 (Q9HA65)
TBC1 domain family member 17
Gene: TBC1D17

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	16923123
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH_RBD~Ras, RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 648
+	Hs
		918951 RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18		TBC17_HUMAN (1-648): 0: 583: 100.00
+	Hs
		592503 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		TBC17_HUMAN (1-648): 0: 583: 100.00
+	Hs
		895381 RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26		TBC17_HUMAN (1-648): 0: 583: 100.00
+	Hs
		844641 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		TBC15_HUMAN (5-639): 0: 539: 46.19
+	Hs
		592392 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		TBC15_HUMAN (5-639): 0: 539: 46.19
+	Hs
		895369 RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26		TBC15_HUMAN (5-639): 0: 539: 46.19
+	Dm
		1358729 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		Q9VPL5_DROME (2-626): 1.98e-125: 389: 30.48
+	Os
		1130874 Q7XHP7_ORYSJ (17-216): 1.07e-88: 261: 38.54		Q5SMT0_ORYSJ (2-600): 8.61e-132: 404: 28.29
+	Os
		1130875 Q84TA8_ORYSJ (17-216): 2.94e-88: 260: 39.22		Q5SMT0_ORYSJ (2-600): 8.61e-132: 404: 28.29
+	Os
		772871 RIC2_ORYSJ (9-215): 6.47e-88: 260: 38.61		Q5SMT0_ORYSJ (2-600): 8.61e-132: 404: 28.29
+	Hs
		592584 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		TBD2B_HUMAN (1-644): 2.21e-103: 338: 15.53
+	Hs
		914465 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		TBD2B_HUMAN (1-644): 2.21e-103: 338: 15.53
+	Hs
		321281 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		TBCD8_HUMAN (137-647): 1.16e-80: 278: 13.60
+	Hs
		234370 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		EVI5_HUMAN (279-615): 9.14e-79: 268: 16.62
+	Hs
		592528 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		TB22B_HUMAN (193-582): 7.25e-80: 263: 18.90
+	Hs
		914423 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		TBC14_HUMAN (214-599): 8.67e-79: 266: 16.96
+	Hs
		914391 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		TB22B_HUMAN (193-582): 7.25e-80: 263: 18.90
+	Hs
		914275 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		EVI5L_HUMAN (205-640): 1.76e-76: 262: 14.71
+	Hs
		233036 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		TBC12_HUMAN (207-582): 1.53e-76: 261: 18.44
+	Hs
		234378 RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89		EVI5_HUMAN (279-615): 9.14e-79: 268: 16.62