HitPredict

Interactor 1: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Interactor 2: HDGR2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)
Gene: HDGFL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1590 Hs			1 671
+	Hs
		846864 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Mm
		1111947 SMCA4_MOUSE (40-1588): 0: 986: 72.81		NSD2_MOUSE (3-440): 2.24e-66: 239: 13.47
+	Hs
		847072 SMCA4_HUMAN (40-1588): 0: 977: 72.70		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		847113 SMCA4_HUMAN (40-1588): 0: 977: 72.70		ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24
+	Hs
		229270 SMCA5_HUMAN (610-1584): 0: 803: 27.43		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		1059699 CHD4_HUMAN (370-1589): 0: 749: 22.31		HDGR2_HUMAN (1-671): 9.52e-82: 274: 100.00
+	Hs
		331813 CHD4_HUMAN (370-1589): 0: 749: 22.31		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		1317720 CHD8_HUMAN (19-1359): 0: 741: 21.67		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		266013 CHD4_HUMAN (370-1589): 0: 749: 22.31		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		266004 CHD3_HUMAN (415-1590): 0: 725: 23.92		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		855558 CHD8_HUMAN (19-1359): 0: 741: 21.67		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		229343 SMCA5_HUMAN (610-1584): 0: 803: 27.43		HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78
+	Hs
		1059940 CHD4_HUMAN (370-1589): 0: 749: 22.31		ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24
+	Hs
		855463 CHD3_HUMAN (415-1590): 0: 725: 23.92		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		1059655 CHD4_HUMAN (370-1589): 0: 749: 22.31		GLYR1_HUMAN (6-212): 3.25e-36: 145: 21.10
+	Hs
		1018748 CHD3_HUMAN (415-1590): 0: 725: 23.92		ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24
+	Hs
		1255051 CHD5_HUMAN (409-1588): 0: 718: 22.36		ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24
+	Hs
		1018514 CHD3_HUMAN (415-1590): 0: 725: 23.92		GLYR1_HUMAN (6-212): 3.25e-36: 145: 21.10
+	Dm
		332845 CHDM_DROME (333-1579): 0: 711: 21.17		Q9VGW4_DROME (57-626): 1.92e-09: 63.3: 12.07