Interactor 1: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 19615732, 19490896
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~Prot_ATP_ID_OB, MitMem_reg~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 324
Hs

1 406
+ At
+ At
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc
+ Sp
+ At
+ Hs
+ Sp
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs
+ Sc
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024