HitPredict

Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.620

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 439 Hs			1 815
+	Mm
		868858 PRS4_MOUSE (32-433): 5.45e-136: 399: 43.60		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		292078 PRS6A_MOUSE (1-439): 2.99e-135: 397: 99.32		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		868859 PRS8_MOUSE (65-437): 1.93e-126: 373: 44.39		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		868838 PRS6B_MOUSE (8-438): 9.32e-118: 352: 37.59		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Hs
		868392 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Mm
		868928 TERA_MOUSE (162-434): 9.21e-77: 256: 35.17		ATX1_MOUSE (1-815): 0: 1271: 86.89