HitPredict

Interactor 1: RGD2 (P43556)
Rho-GTPase-activating protein RGD2
Gene: RGD2

Interactor 2: RHO5 (P53879)
GTP-binding protein RHO5
Gene: RHO5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11591390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0007264 - small GTPase-mediated signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 714 Sc			1 331
+	Sc
		618353 RGD2_YEAST (1-714): 0: 833: 100.00		CDC42_YEAST (1-229): 2.42e-76: 234: 42.80
+	Hs
		962634 PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11		RHOA_HUMAN (5-229): 2.66e-77: 236: 40.89
+	Hs
		988825 PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11		RAC1_HUMAN (1-229): 2.72e-75: 231: 44.11
+	Hs
		953758 PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11		RAC3_HUMAN (1-218): 1.77e-72: 224: 44.95
+	Hs
		1015904 PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11		RHOG_HUMAN (1-229): 2.29e-72: 223: 41.92
+	Hs
		955755 PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11		CDC42_HUMAN (1-229): 2.85e-70: 218: 44.11
+	Hs
		962619 PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29		RHOA_HUMAN (5-229): 2.66e-77: 236: 40.89
+	Hs
		988810 PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29		RAC1_HUMAN (1-229): 2.72e-75: 231: 44.11
+	Hs
		953750 PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29		RAC3_HUMAN (1-218): 1.77e-72: 224: 44.95
+	Hs
		955740 PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29		CDC42_HUMAN (1-229): 2.85e-70: 218: 44.11
+	Hs
		601498 PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11		RHOQ_HUMAN (4-222): 7.28e-56: 182: 42.92
+	Hs
		601490 PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29		RHOQ_HUMAN (4-222): 7.28e-56: 182: 42.92
+	Hs
		988631 FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29		RAC1_HUMAN (1-229): 2.72e-75: 231: 44.11
+	Hs
		955197 CIP4_HUMAN (9-390): 1.86e-59: 212: 14.76		CDC42_HUMAN (1-229): 2.85e-70: 218: 44.11
+	Hs
		953627 FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29		RAC3_HUMAN (1-218): 1.77e-72: 224: 44.95
+	Hs
		1015698 FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29		RHOG_HUMAN (1-229): 2.29e-72: 223: 41.92
+	Hs
		955501 FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29		CDC42_HUMAN (1-229): 2.85e-70: 218: 44.11
+	Hs
		953492 FBP1L_HUMAN (9-226): 1.03e-51: 191: 14.80		RAC3_HUMAN (1-218): 1.77e-72: 224: 44.95
+	Hs
		601302 CIP4_HUMAN (9-390): 1.86e-59: 212: 14.76		RHOQ_HUMAN (4-222): 7.28e-56: 182: 42.92
+	Hs
		601413 FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29		RHOQ_HUMAN (4-222): 7.28e-56: 182: 42.92