HitPredict

Interactor 1: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 22037170, 11805826, 26182356, 31487956, 14759368, 16284124, 16338358, 22215586, 24038880, 26450923, 16554755, 16429126, 28106073, 26929360, 37968396, 34161281, 27405762, 31601863, 31848235, 30792173 and 9 others

more...
Identification Methods pull down, tandem affinity purification, affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 306
Sc

1 405
+ Sp
+ At
+ Dm
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Sp
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025