HitPredict

Interactor 1: KS6A3 (P51812)
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
Gene: RPS6KA3

Interactor 2: APBA1 (Q02410)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007268 - chemical synaptic transmission
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 837
+	Hs
		850651 KS6A3_HUMAN (1-740): 0: 844: 100.00		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46
+	Hs
		942348 KS6A1_HUMAN (1-740): 0: 783: 77.90		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		1073444 KS6A1_HUMAN (1-740): 0: 783: 77.90		MAGI2_HUMAN (111-754): 3.59e-20: 98.7: 10.69
+	Hs
		1049960 KS6A1_HUMAN (1-740): 0: 783: 77.90		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46
+	Mm
		1143553 KS6A2_MOUSE (7-327): 4.77e-104: 336: 24.93		DLG4_MOUSE (358-759): 6.84e-28: 122: 13.19
+	Hs
		1021498 KS6A2_HUMAN (7-327): 3.91e-100: 326: 24.02		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Hs
		1049957 KS6A2_HUMAN (7-327): 3.91e-100: 326: 24.02		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46