Protein: ROM2
RHO1 GDP-GTP exchange protein 2

Gene: ROM2
Organism: Saccharomyces cerevisiae S288C
Interactions: 57
UniProt ID: P51862

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448555

RHO1
GTP-binding protein RHO1

3

20

Small-scale

0.858

High

366823

IPYR
Inorganic pyrophosphatase

4

2

High-throughput

0.694

High

908520

ACK1
Activator of C kinase protein 1

4

1

High-throughput

0.633

High

908513

SLT2
Mitogen-activated protein kinase SLT2/MPK1

2

9

Small-scale

0.619

High

908507

ROM1
RHO1 GDP-GTP exchange protein 1

1

17

High-throughput

0.618

High

908517

TUS1
Rho1 guanine nucleotide exchange factor TUS1

1

17

High-throughput

0.618

High

908510

WSC2
Cell wall integrity and stress response component 2

2

4

High-throughput

0.613

High

553633

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

High-throughput

0.595

High

453973

IF4E
Eukaryotic translation initiation factor 4E

2

0

High-throughput

0.576

High

510653

HSP77
Import motor subunit, mitochondrial

2

6

High-throughput

0.571

High

725733

RM09
Large ribosomal subunit protein uL3m

2

1

High-throughput

0.567

High

545550

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.536

High

722098

XPO1
Exportin-1

1

14

High-throughput

0.536

High

823130

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.513

High

908521

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.513

High

779864

MID2
Cell wall integrity sensor MID2

1

3

Small-scale

0.508

High

908512

SLG1
Protein SLG1

1

1

Small-scale

0.508

High

908508

MTL1
Protein MTL1

1

6

Small-scale

0.504

High

602558

PHO85
Cyclin-dependent protein kinase PHO85

1

2

Small-scale

0.501

High

751433

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.493

High

763091

RRP1
Ribosomal RNA-processing protein 1

1

0

High-throughput

0.493

High

816865

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.493

High

908509

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.493

High

864262

ALY2
Arrestin-related trafficking adapter 3

1

4

Small-scale

0.481

High

667040

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

393033

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

707634

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

741004

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

792870

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

893426

ZDS1
Protein ZDS1

1

1

High-throughput

0.479

High

664319

SSD1
Protein SSD1

1

0

Small-scale

0.458

High

746296

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

757990

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.458

High

826656

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

908515

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

908516

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

908518

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

394716

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

524550

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

527166

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

592365

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

670923

SIS1
Protein SIS1

1

7

High-throughput

0.445

High

676164

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.445

High

741970

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

804300

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

811354

CAJ1
Protein CAJ1

1

10

High-throughput

0.445

High

816306

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.445

High

824488

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

826454

DJP1
DnaJ-like protein 1

1

11

High-throughput

0.445

High

908506

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

908514

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

626813

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.407

High

850641

ERJ5
ER-localized J domain-containing protein 5

1

9

High-throughput

0.407

High

908511

FAR11
Factor arrest protein 11

2

0

High-throughput

0.307

High

858312

NUP85
Nucleoporin NUP85

1

0

High-throughput

0.279

Low

908519

NDH2
External NADH-ubiquinone oxidoreductase 2, mitochondrial

1

0

High-throughput

0.269

Low

739694

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025