HitPredict

Interactor 1: C9E8W1 (C9E8W1)
HLA-C alpha chain (Cw*1701) (MHC class I antigen)
Gene: HLA-Cw

Interactor 2: KI2L2 (P43627)
Killer cell immunoglobulin-like receptor 2DL2 (CD158 antigen-like family member B1) (Natural killer-associated transcript 6) (NKAT-6) (p58 natural killer cell receptor clone CL-43) (p58 NK receptor CL-43) (CD antigen CD158b1)
Gene: KIR2DL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	18322206
Identification Methods	affinity chromatography technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 348
+	Hs
		850806 Q5RIP0_HUMAN (1-372): 1.51e-166: 471: 90.86		KI2L2_HUMAN (1-348): 3.64e-135: 390: 100.00
+	Hs
		850781 Q5RIP0_HUMAN (1-372): 1.51e-166: 471: 90.86		KI2L1_HUMAN (1-348): 3.23e-133: 385: 94.54
+	Hs
		850779 Q5D1W8_HUMAN (1-372): 5.28e-165: 467: 90.59		KI2L1_HUMAN (1-348): 3.23e-133: 385: 94.54
+	Hs
		409455 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		LIRB4_HUMAN (1-324): 4.85e-78: 247: 29.20
+	Hs
		1133831 Q95J06_HUMAN (1-371): 5.5e-179: 503: 77.90		KI3S1_HUMAN (1-346): 2.19e-71: 228: 31.23
+	Hs
		409383 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		KI3S1_HUMAN (1-346): 2.19e-71: 228: 31.23
+	Hs
		47606 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		A0A8I5QEB2_HUMAN (1-330): 1.42e-68: 222: 34.23
+	Hs
		1133828 Q5SUL5_HUMAN (1-371): 3.25e-170: 480: 78.44		KI3S1_HUMAN (1-346): 2.19e-71: 228: 31.23
+	Hs
		409302 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		KI3L2_HUMAN (1-347): 3.24e-67: 220: 32.57
+	Hs
		850877 Q5S3G3_HUMAN (1-371): 1.41e-172: 486: 80.32		KI3L2_HUMAN (1-347): 3.24e-67: 220: 32.57
+	Hs
		1325618 Q95J06_HUMAN (1-371): 5.5e-179: 503: 77.90		LIRB2_HUMAN (17-348): 7.39e-54: 188: 28.70
+	Hs
		1340138 Q95J06_HUMAN (1-371): 5.5e-179: 503: 77.90		LIRB1_HUMAN (14-348): 6.89e-52: 183: 28.16
+	Hs
		409446 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		LIRB2_HUMAN (17-348): 7.39e-54: 188: 28.70
+	Hs
		1209905 Q5S3G3_HUMAN (1-371): 1.41e-172: 486: 80.32		LIRB2_HUMAN (17-348): 7.39e-54: 188: 28.70
+	Hs
		409456 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		LIRB1_HUMAN (14-348): 6.89e-52: 183: 28.16
+	Hs
		1209906 Q5S3G3_HUMAN (1-371): 1.41e-172: 486: 80.32		LIRB1_HUMAN (14-348): 6.89e-52: 183: 28.16
+	Hs
		850828 Q5S3G3_HUMAN (1-371): 1.41e-172: 486: 80.32		KI2L3_HUMAN (124-346): 1.8e-29: 117: 24.78
+	Hs
		850913 Q5S3G3_HUMAN (1-371): 1.41e-172: 486: 80.32		KI2S4_HUMAN (124-346): 4.9e-29: 115: 24.67
+	Hs
		850827 Q5RIP0_HUMAN (1-372): 1.51e-166: 471: 90.86		KI2L3_HUMAN (124-346): 1.8e-29: 117: 24.78
+	Hs
		409294 HLAA_HUMAN (1-371): 1.89e-173: 488: 80.32		CEAM6_HUMAN (13-311): 8.89e-21: 93.4: 12.98