HitPredict

Interactor 1: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	26496610, 33961781, 35271311, 32960270
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 529 Hs			1 790
+	Hs
		134884 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		131422 IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		238663 IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		853578 IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Sc
		710205 IMA1_YEAST (2-529): 3.96e-141: 419: 43.83		NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53