HitPredict

Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Interactor 2: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40) (rpL40)]
Gene: UBA52

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	38334954, 31839598, 26414014
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 128
+	Hs
		853454 UBP5_HUMAN (1-858): 0: 847: 100.00		RS27A_HUMAN (1-77): 4.85e-38: 127: 98.70
+	Hs
		507109 UBP5_HUMAN (1-858): 0: 847: 100.00		UBB_HUMAN (1-76): 5.79e-33: 117: 100.00
+	Dm
		583723 Q9VZU7_DROME (7-855): 0: 637: 49.14		RS27A_DROME (1-77): 9.34e-38: 127: 98.70
+	At
		1167722 UBP14_ARATH (7-856): 0: 611: 46.57		UBQ3_ARATH (1-77): 7.33e-35: 123: 94.81
+	Sc
		509891 UBP14_YEAST (11-855): 9.16e-126: 398: 26.82		RL40A_YEAST (1-128): 1.82e-52: 163: 89.84
+	Hs
		987434 USP9X_HUMAN (289-795): 1.16e-86: 305: 14.26		RL40_HUMAN (1-128): 1.49e-55: 171: 100.00
+	Hs
		987435 UBP7_HUMAN (247-777): 1e-83: 292: 13.54		RL40_HUMAN (1-128): 1.49e-55: 171: 100.00
+	Hs
		967139 UBP46_HUMAN (292-681): 5.47e-80: 264: 13.71		RL40_HUMAN (1-128): 1.49e-55: 171: 100.00
+	Rn
		98870 UBP46_RAT (292-681): 5.64e-80: 264: 13.71		RL40_RAT (1-128): 1.49e-55: 171: 100.00
+	Hs
		987144 USP9X_HUMAN (289-795): 1.16e-86: 305: 14.26		RS27A_HUMAN (1-77): 4.85e-38: 127: 98.70
+	Hs
		987252 UBP36_HUMAN (251-817): 3.49e-86: 299: 14.12		RS27A_HUMAN (1-77): 4.85e-38: 127: 98.70
+	Hs
		507299 UBP7_HUMAN (247-777): 1e-83: 292: 13.54		UBB_HUMAN (1-76): 5.79e-33: 117: 100.00
+	At
		1168008 UBP12_ARATH (235-743): 3.85e-81: 285: 14.79		UBQ3_ARATH (1-77): 7.33e-35: 123: 94.81
+	Hs
		288434 UBP2_HUMAN (281-660): 3.14e-79: 269: 14.18		Q5U5U6_HUMAN (1-76): 5.79e-33: 117: 100.00
+	Hs
		507144 UBP46_HUMAN (292-681): 5.47e-80: 264: 13.71		UBB_HUMAN (1-76): 5.79e-33: 117: 100.00